Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 5/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11511071 | 0.90 | KDM4E (0.57) | KDM4EMEN1KMT2ATSHRALOX15 | |
| SCHEMBL11510029 | 0.82 | ALDH1A1 (0.52) | KDM4EMEN1KMT2AMAPK1ALDH1A1 | |
| SCHEMBL9402280 | 0.81 | KDM4E (0.70) | KDM4EMEN1KMT2ATSHRALOX15 | |
| SCHEMBL11511765 | 0.78 | NPC1 (0.53) | MEN1KMT2AALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL10432414 | 0.74 | OPRK1 (0.64) | KDM4EMEN1KMT2ATSHRALDH1A1 | |
| SCHEMBL11512132 | 0.74 | DRD2 (0.78) | MEN1KMT2AALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL9402219 | 0.74 | — | — | |
| SCHEMBL6406195 | 0.73 | KDM4E (0.74) | KDM4EMEN1KMT2ATSHRALOX15 | |
| SCHEMBL11509955 | 0.73 | TSHR (0.43) | MEN1KMT2ATSHRALDH1A1HTT | |
| SCHEMBL11512453 | 0.73 | ALDH1A1 (0.51) | MEN1KMT2ATSHRALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4178253-A | 1,2,4-TRIAZOLE COMPOUNDS | CIBA-GEIGY CORPORATION (US) | 1979-12-11 | — | — | US | disclosed |