Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.64 |
| ▸ | GAA | P10253 | 1/20 | 0.64 |
| ▸ | HPGD | P15428 | 1/20 | 0.64 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.64 |
| ▸ | GLO1 | Q04760 | 6/20 | 0.59 |
| ▸ | MEN1 | O00255 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | ATM | Q13315 | 2/20 | 0.55 |
| ▸ | CASP6 | P55212 | 1/20 | 0.55 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.55 |
| ▸ | ATIC | P31939 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11511844 | 1.00 | LMNA (0.64) | LMNAL3MBTL1GAAHPGDNPSR1 | |
| SCHEMBL2203510 | 0.87 | ATIC (0.69) | LMNAL3MBTL1GAAHPGDNPSR1 | |
| SCHEMBL29933125 | 0.87 | ATIC (0.69) | LMNAL3MBTL1GAAHPGDNPSR1 | |
| SCHEMBL31658970 | 0.87 | ATIC (0.69) | LMNAL3MBTL1GAAHPGDNPSR1 | |
| SCHEMBL2203513 | 0.87 | ATIC (0.69) | LMNAL3MBTL1GAAHPGDNPSR1 | |
| SCHEMBL29352135 | 0.85 | MEN1 (0.65) | LMNAL3MBTL1GAAHPGDNPSR1 | |
| SCHEMBL9645286 | 0.85 | MEN1 (0.65) | LMNAL3MBTL1GAAHPGDNPSR1 | |
| SCHEMBL11411897 | 0.85 | ATIC (0.67) | LMNAL3MBTL1GAAHPGDNPSR1 | |
| SCHEMBL3083351 | 0.85 | MEN1 (0.65) | LMNAL3MBTL1GAAHPGDNPSR1 | |
| SCHEMBL1309169 | 0.84 | L3MBTL1 (0.63) | LMNAL3MBTL1GAAHPGDNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4176009-A | HYDROLYZING OLIGOPEPTIDES IN A AQUEOUS SOLUTION TO RELEASE PEPTIDE FRAGMENTS, USING COLORIMETRIC ANALYSIS AFTER SOLVENT EXTRACTION | AJINOMOTO CO., INC. (JP) | 1979-11-27 | — | — | US | disclosed |
| US-4138394-A | Peptide derivatives and a method of measuring collagenase activity | AJINOMOTO CO., INC. (JP) | 1979-02-06 | — | — | US | disclosed |