Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB known ✓ | P10828 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.65 |
| ▸ | MAPT | P10636 | 3/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.65 |
| ▸ | POLB | P06746 | 1/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.65 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | GAA | P10253 | 1/20 | 0.64 |
| ▸ | HPGD | P15428 | 1/20 | 0.64 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.64 |
| ▸ | GLO1 | Q04760 | 3/20 | 0.59 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.57 |
| ▸ | DUSP5 | Q16690 | 1/20 | 0.57 |
| ▸ | ATIC | P31939 | 1/20 | 0.53 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | ATM | Q13315 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9645286 | 1.00 | MEN1 (0.65) | MEN1KMT2AMAPTTDP1POLB | |
| SCHEMBL3083351 | 1.00 | MEN1 (0.65) | MEN1KMT2AMAPTTDP1POLB | |
| SCHEMBL29933125 | 0.87 | ATIC (0.69) | MEN1KMT2AMAPTTDP1POLB | |
| SCHEMBL31658970 | 0.87 | ATIC (0.69) | MEN1KMT2AMAPTTDP1POLB | |
| SCHEMBL2203513 | 0.87 | ATIC (0.69) | MEN1KMT2AMAPTTDP1POLB | |
| SCHEMBL2203510 | 0.87 | ATIC (0.69) | MEN1KMT2AMAPTTDP1POLB | |
| SCHEMBL11511844 | 0.85 | LMNA (0.64) | MEN1KMT2AMAPTTDP1POLB | |
| SCHEMBL11411897 | 0.85 | ATIC (0.67) | MEN1KMT2AMAPTTDP1POLB | |
| SCHEMBL11511843 | 0.85 | LMNA (0.64) | MEN1KMT2AMAPTTDP1POLB | |
| SCHEMBL1309169 | 0.84 | L3MBTL1 (0.63) | MEN1KMT2AMAPTTDP1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1776 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4701617-A1 | METHOD FOR DYEING KERATIN FIBERS, COMPRISING THE USE OF A DYE CONTAINING CHITOSANE AND A DYEING COMPOUND, AND THE USE OF AN AFTERTREATMENT AGENT CONTAINING PROTEIN HYDROLYSATE AND/OR AMINO ACID | Henkel AG & Co. KGaA (DE) | 2026-03-04 | — | — | EP | claimed |
| EP-4701618-A1 | METHOD FOR DYEING KERATIN FIBERS, COMPRISING THE USE OF A DYE CONTAINING CHITOSANE AND A DYEING COMPOUND, AND THE USE OF A SHAMPOO | Henkel AG & Co. KGaA (DE) | 2026-03-04 | — | — | EP | claimed |
| EP-3723864-B1 | THICKENED ONE-COMPONENT HAIR TONER | HENKEL AG & CO KGAA (DE) | 2026-01-14 | — | — | EP | claimed |
| CN-114874862-B | Apparatus for surface cleaning and related compositions and methods | 金诺斯公司 | 2025-05-30 | — | — | CN | claimed |
| WO-2025078062-A1 | METHOD FOR SYNTHETIZING POLYMERIC DYES | DOVER EUROPE SÀRL (CH) | 2025-04-17 | — | — | WO | claimed |
| EP-4538329-A1 | METHOD FOR SYNTHETIZING POLYMERIC DYES | Dover Europe Sàrl (CH) | 2025-04-16 | — | — | EP | claimed |
| CN-119823482-A | High-temperature-resistant glass fiber reinforced PP composite material and preparation process thereof | 苏州润佳工程塑料股份有限公司 | 2025-04-15 | — | — | CN | claimed |
| EP-3873416-B1 | METHOD FOR TREATING HAIR, COMPRISING THE APPLICATION OF A FIRST AGENT (A) HAVING A SILANE AND A CHROMOPHORIC COMPOUND, AND A SECOND AGENT (B) HAVING A FILM-FORMING POLYMER | HENKEL AG & CO KGAA (DE) | 2025-02-26 | — | — | EP | claimed |
| EP-3873402-B1 | METHOD FOR TREATING HAIR, COMPRISING THE APPLICATION OF AN ORGANIC SILICON COMPOUND, AN ALKALISING AGENT AND A FILM-FORMING POLYMER | HENKEL AG & CO KGAA (DE) | 2025-02-26 | — | — | EP | claimed |
| CN-119490716-A | High-performance rubber sealing ring material and preparation method thereof | 蚌埠市振中橡塑制品有限公司 | 2025-02-21 | — | — | CN | claimed |
| CN-113754568-B | Acid orange I hapten, artificial antigen, synthesis and application thereof | 江南大学 | 2022-05-17 | — | — | CN | claimed |
| US-20220143251-A1 | Device and Related Compositions and Methods for Use in Surface Decontamination | KINNOS INC (US) | 2022-05-12 | — | — | US | claimed |
| EP-3989920-A1 | ADDITIVES FOR COLORING AGENTS AND METHODS OF USE THEREOF | Living Proof, Inc. (US) | 2022-05-04 | — | — | EP | claimed |
| CN-114388077-A | Traditional Chinese medicine dyed material database based on micro-focusing Raman technology and application thereof in identification of traditional Chinese medicine dyed materials | 成都市食品药品检验研究院 | 2022-04-22 | — | — | CN | claimed |
| CN-109715777-B | Apparatus for surface decontamination and related compositions and methods | 金诺斯公司 | 2022-04-19 | — | — | CN | claimed |
| CN-114341325-A | Solid detergent composition | 联合利华知识产权控股有限公司 | 2022-04-12 | — | — | CN | claimed |
| US-11291622-B2 | Method for dyeing keratinous material, comprising the use of an organosilicon compound, a dyeing compound and a silicon oil | HENKEL AG & CO. KGAA (DE) | 2022-04-05 | — | — | US | claimed |
| CN-114222555-A | Additives for colorants and methods of use thereof | 生活实验公司 | 2022-03-22 | — | — | CN | claimed |
| CN-114213900-A | Watercolor ink capable of halation dyeing and multiple color folding and paper breaking and preparation method thereof | 广东肇庆市红鹰科技有限公司 | 2022-03-22 | — | — | CN | claimed |
| CN-110243980-B | High-throughput detection method for 92 forbidden industrial dyes in food | 宁波出入境检验检疫局检验检疫技术中心 | 2022-03-11 | — | — | CN | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11291622-B2 | Method for dyeing keratinous material, comprising the use of an organosilicon compound, a dyeing compound and a silicon oil | KRT18, MKI67, DSG1 | THRB 4573/4885MEN1 665/4885KMT2A 987/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.