Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | DRD4 | P21917 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA3 | P07451 | 1/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
| ▸ | CA6 | P23280 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11512589 | 0.84 | KMT2A (0.39) | GAAKMT2AMEN1LMNAHTT | |
| SCHEMBL11513892 | 0.82 | LMNA (0.36) | ALDH1A1KMT2ASMN1; SMN2LMNAHTT | |
| SCHEMBL9628933 | 0.78 | TSHR (0.45) | KMT2ASMN1; SMN2LMNACA12CA1 | |
| SCHEMBL11513318 | 0.77 | ALDH1A1 (0.40) | ALDH1A1KMT2ASMN1; SMN2NPC1HTT | |
| SCHEMBL11242674 | 0.77 | LMNA (0.40) | ALDH1A1GAAKMT2AMEN1POLB | |
| SCHEMBL11512525 | 0.76 | HTT (0.56) | ALDH1A1GAAKMT2AMEN1POLB | |
| SCHEMBL9587421 | 0.74 | LMNA (0.38) | ALDH1A1KMT2APOLBLMNACA12 | |
| SCHEMBL11245719 | 0.73 | LMNA (0.37) | ALDH1A1KMT2APOLBLMNACA12 | |
| SCHEMBL9821185 | 0.72 | TSHR (0.39) | KMT2ASMN1; SMN2LMNACA12CA1 | |
| SCHEMBL2757972 | 0.70 | HTT (0.55) | ALDH1A1GAAALOX15GFERKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4162325-A | PHARMACEUTICAL ACTIVITY ON THE MNEMIC PROCESSES | UCB, SOCIETE ANONYME (BE) | 1979-07-24 | — | — | US | disclosed |