Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA3 | P07451 | 1/20 | 0.34 |
| ▸ | CA4 | P22748 | 1/20 | 0.34 |
| ▸ | CA6 | P23280 | 1/20 | 0.34 |
| ▸ | CA5A | P35218 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11512589 | 0.85 | KMT2A (0.39) | LMNAPIK3CDKMT2ACA12CA1 | |
| SCHEMBL11512062 | 0.82 | ALDH1A1 (0.38) | LMNAKMT2ACA12CA1CA2 | |
| SCHEMBL9628933 | 0.79 | TSHR (0.45) | LMNAPIK3CDCHRM5CHRM3KMT2A | |
| SCHEMBL11513318 | 0.79 | ALDH1A1 (0.40) | KMT2AALDH1A1HTTCYP1A2KDM4E | |
| SCHEMBL11242674 | 0.78 | LMNA (0.40) | LMNAPIK3CDCHRM5CHRM3KMT2A | |
| SCHEMBL11512525 | 0.78 | HTT (0.56) | LMNACHRM3KMT2AALDH1A1HTT | |
| SCHEMBL9587421 | 0.75 | LMNA (0.38) | LMNAPIK3CDCHRM5CHRM3KMT2A | |
| SCHEMBL11245719 | 0.74 | LMNA (0.37) | LMNAPIK3CDKMT2ACA12CA1 | |
| SCHEMBL9821185 | 0.74 | TSHR (0.39) | LMNACHRM5CHRM3KMT2ACA12 | |
| SCHEMBL10350531 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4162325-A | PHARMACEUTICAL ACTIVITY ON THE MNEMIC PROCESSES | UCB, SOCIETE ANONYME (BE) | 1979-07-24 | — | — | US | claimed |
| US-4162325-A | PHARMACEUTICAL ACTIVITY ON THE MNEMIC PROCESSES | UCB, SOCIETE ANONYME (BE) | 1979-07-24 | — | — | US | disclosed |