Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 6/20 | 0.43 |
| ▸ | GABRA5 | P31644 | 6/20 | 0.43 |
| ▸ | GABRA3 | P34903 | 6/20 | 0.43 |
| ▸ | GABRA2 | P47869 | 6/20 | 0.43 |
| ▸ | GABRB2 | P47870 | 6/20 | 0.43 |
| ▸ | GABRG2 | P18507 | 4/20 | 0.43 |
| ▸ | GABRB3 | P28472 | 4/20 | 0.43 |
| ▸ | GABRP | O00591 | 3/20 | 0.43 |
| ▸ | GABRD | O14764 | 3/20 | 0.43 |
| ▸ | GABRB1 | P18505 | 3/20 | 0.43 |
| ▸ | GABRA4 | P48169 | 3/20 | 0.43 |
| ▸ | GABRE | P78334 | 3/20 | 0.43 |
| ▸ | GABRA6 | Q16445 | 3/20 | 0.43 |
| ▸ | GABRG1 | Q8N1C3 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11508834 | 0.84 | LMNA (0.61) | LMNAMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL7315953 | 0.84 | GABRA1 (0.60) | LMNAMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL7412915 | 0.80 | PDE4D (0.59) | LMNAMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL11508404 | 0.78 | GABRA1 (0.58) | LMNAMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL11020111 | 0.77 | GABRA1 (0.62) | LMNAHPGDGABRA1GABRA5GABRA3 | |
| SCHEMBL11510293 | 0.77 | LMNA (0.46) | LMNAMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL9384372 | 0.72 | GABRA1 (0.57) | LMNAMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL5432261 | 0.72 | GABRA1 (0.61) | LMNAMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL8928431 | 0.72 | GABRA1 (0.54) | LMNAMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL11507176 | 0.70 | CHRM1 (0.61) | LMNAALDH1A1NPSR1GABRA1GABRA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4155913-A | ANTICONBULSANTS, MUSCLE RELAXANTS AND SEDATIVES | HOFFMANN-LA ROCHE INC. (US) | 1979-05-22 | — | — | US | disclosed |