Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.32 |
| ▸ | ASPH | Q12797 | 1/20 | 0.32 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.32 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.32 |
| ▸ | HIF1AN | Q9NWT6 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11512571 | 0.87 | TSHR (0.41) | LMNAKMT2ATSHRUSP2MAPT | |
| SCHEMBL11513362 | 0.81 | NLRP3 (0.40) | KMT2ATSHR | |
| SCHEMBL8300486 | 0.75 | TSHR (0.34) | TSHR | |
| SCHEMBL8912155 | 0.75 | TSHR (0.34) | TSHR | |
| SCHEMBL8301176 | 0.71 | HTT (0.36) | LMNAKMT2AUSP2HTT | |
| SCHEMBL8300720 | 0.71 | HTT (0.35) | KMT2AUSP2HTT | |
| SCHEMBL27661365 | 0.70 | TSHR (0.38) | LMNAKMT2ATSHRHTTMAPT | |
| SCHEMBL9206004 | 0.67 | HTT (0.59) | LMNAKMT2ATSHRHTT | |
| SCHEMBL8912293 | 0.66 | FPR3 (0.35) | MAPT | |
| SCHEMBL8300377 | 0.66 | FPR3 (0.35) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4162325-A | PHARMACEUTICAL ACTIVITY ON THE MNEMIC PROCESSES | UCB, SOCIETE ANONYME (BE) | 1979-07-24 | — | — | US | disclosed |