Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.40 |
| ▸ | PPID | Q08752 | 4/20 | 0.38 |
| ▸ | PPIB | P23284 | 1/20 | 0.38 |
| ▸ | PPIA | P62937 | 1/20 | 0.38 |
| ▸ | PPIG | Q13427 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11512294 | 0.81 | MME (0.41) | KMT2ATSHR | |
| SCHEMBL11512571 | 0.80 | TSHR (0.41) | KMT2AAVPR2TSHR | |
| SCHEMBL27660443 | 0.74 | ALDH1A1 (0.38) | MEN1KMT2ATSHRALDH1A1 | |
| SCHEMBL11512938 | 0.72 | HTT (0.48) | NLRP3MEN1KMT2AGAAKDM4E | |
| SCHEMBL8301176 | 0.71 | HTT (0.36) | KMT2AALDH1A1 | |
| SCHEMBL11512914 | 0.70 | GAA (0.43) | NLRP3MEN1KMT2AGAAKDM4E | |
| SCHEMBL6159601 | 0.70 | ALDH1A1 (0.36) | MEN1KMT2AALDH1A1 | |
| SCHEMBL6159606 | 0.70 | OPRM1 (0.42) | MEN1KMT2AALDH1A1 | |
| SCHEMBL11512936 | 0.70 | LMNA (0.43) | NLRP3PPIDGAAKDM4EHSD17B10 | |
| SCHEMBL24176272 | 0.70 | KDM4E (0.37) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4162325-A | PHARMACEUTICAL ACTIVITY ON THE MNEMIC PROCESSES | UCB, SOCIETE ANONYME (BE) | 1979-07-24 | — | — | US | disclosed |