Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11512571 | 0.88 | TSHR (0.41) | TSHRAVPR2 | |
| SCHEMBL8300486 | 0.85 | TSHR (0.34) | TSHRAVPR2 | |
| SCHEMBL8913129 | 0.81 | INMT (0.33) | TSHR | |
| SCHEMBL6160221 | 0.80 | KMT2A (0.33) | — | |
| SCHEMBL8912293 | 0.78 | FPR3 (0.35) | — | |
| SCHEMBL6158568 | 0.76 | HSD11B1 (0.37) | — | |
| SCHEMBL11512294 | 0.75 | MME (0.41) | TSHR | |
| SCHEMBL8300521 | 0.73 | SMN1; SMN2 (0.45) | — | |
| SCHEMBL6160923 | 0.73 | MAPT (0.32) | — | |
| SCHEMBL6159601 | 0.73 | ALDH1A1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0808303-A1 | 5-(4-SUBST.-PIPERIDINYL-1)-3-ARYL-PENTANOIC ACID DERIVATIVES AS TACHYKININ RECEPTOR ANTAGONIST | ZENECA LIMITED (GB) | 1997-11-26 | — | — | EP | disclosed |
| WO-1996024582-A1 | 5-(4-SUBST.-PIPERIDINYL-1)-3-ARYL-PENTANOIC ACID DERIVATIVES AS TACHYKININ RECEPTOR ANTAGONIST | ZENECA LIMITED (GB) | 1996-08-15 | — | — | WO | disclosed |