Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 3/20 | 0.46 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 10/20 | 0.37 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.33 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.33 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8973534 | 0.72 | CA12 (0.56) | HMGCREPHX2MAPT | |
| SCHEMBL8766175 | 0.71 | CA12 (0.57) | HMGCREPHX2GAA | |
| SCHEMBL7119145 | 0.69 | HMGCR (0.46) | HMGCRNR1I2GAAHTTMAPT | |
| SCHEMBL9418530 | 0.68 | HMGCR (0.60) | HMGCRNR1I2GAAMAPT | |
| SCHEMBL8011719 | 0.68 | HMGCR (0.51) | HMGCRNR1I2EPHX2GAAHTT | |
| SCHEMBL465622 | 0.68 | ALDH1A1 (0.40) | CACNA1ACACNA2D1CACNB1GAAPKM | |
| SCHEMBL13599599 | 0.67 | HMGCR (0.40) | HMGCRNR1I2GAAPKMHTT | |
| SCHEMBL8766613 | 0.67 | HMGCR (0.49) | HMGCRNR1I2GAAMAPT | |
| SCHEMBL5668355 | 0.66 | HMGCR (0.58) | HMGCRNR1I2GAAMAPT | |
| SCHEMBL9461314 | 0.66 | CYP2D6 (0.38) | CACNA1ACACNA2D1CACNB1GAAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4152452-A | N-BENZYLANILINE AND DERIVATIVES | WILLIAM H. RORER, INC. (US) | 1979-05-01 | — | — | US | disclosed |