SCHEMBL465622

SCHEMBL465622

CN1C(C)(C)CC(C(c2cc(C(C)(C)C)c(O)c(C(C)(C)C)c2)C2CC(C)(C)N(C)C(C)(C)C2)CC1(C)C

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.40
KDM4E B2RXH2 5/20 0.40
MAPT P10636 4/20 0.40
GAA P10253 3/20 0.40
LMNA P02545 2/20 0.40
TSHR P16473 2/20 0.40
ALOX15 P16050 2/20 0.40
PKM P14618 1/20 0.40
ALOX12 P18054 1/20 0.40
HSD17B10 Q99714 1/20 0.40
CA2 P00918 3/20 0.39
CA1 P00915 2/20 0.39
SMN1; SMN2 Q16637 2/20 0.38
POLB P06746 2/20 0.38
TYR P14679 1/20 0.38
IDH1 O75874 1/20 0.37
MEN1 O00255 1/20 0.36
GALR3 O60755 1/20 0.36
HTT P42858 1/20 0.36
KMT2A Q03164 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2024345 0.79 CACNA1A (0.39) ALDH1A1KDM4EMAPTGAALMNA
SCHEMBL2687906 0.77 CACNA1A (0.34) ALDH1A1KDM4EMAPTGAALMNA
SCHEMBL465621 0.76 ALDH1A1 (0.41) ALDH1A1KDM4EMAPTGAALMNA
SCHEMBL3683968 0.75 HMGCR (0.41) ALDH1A1KDM4EMAPTGAALMNA
SCHEMBL3683965 0.75 ALDH1A1 (0.39) ALDH1A1KDM4EMAPTGAALMNA
SCHEMBL314423 0.75 HIF1A (0.43) ALDH1A1KDM4EMAPTGAALMNA
SCHEMBL28878718 0.75 HTT (0.41) ALDH1A1MAPTGAALMNATSHR
SCHEMBL30712631 0.75 ALDH1A1 (0.47) ALDH1A1KDM4EMAPTGAALMNA
SCHEMBL9461314 0.74 CYP2D6 (0.38) ALDH1A1KDM4EMAPTGAALMNA
SCHEMBL7030387 0.74 IDH1 (0.35) ALDH1A1KDM4EMAPTGAALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3933002-B1 ACTINIC-RAY-CURABLE COATING COMPOSITION, CURED COATING FILM, COATED ARTICLE, AND METHOD FOR FORMING COATING FILM KANSAI PAINT CO LTD (JP) 2024-06-12 EP disclosed
US-20220119668-A1 ACTINIC-RAY-CURABLE COATING COMPOSITION, CURED COATING FILM, COATED ARTICLE, AND METHOD FOR FORMING COATING FILM KANSAI PAINT CO., LTD. (JP) 2022-04-21 US disclosed
EP-3933002-A1 ACTINIC-RAY-CURABLE COATING COMPOSITION, CURED COATING FILM, COATED ARTICLE, AND METHOD FOR FORMING COATING FILM Kansai Paint Co., Ltd (JP) 2022-01-05 EP disclosed
US-20180312697-A1 ACTINIC-RAY-CURABLE COATING COMPOSITION KANSAI PAINT CO., LTD. (JP) 2018-11-01 US disclosed
US-8815987-B2 Polypropylene mineral compound with reduced volatiles BOREALIS AG (AT) 2014-08-26 US disclosed
EP-2445957-B1 POLYPROPYLENE MINERAL COMPOUND WITH REDUCED VOLATILES BOREALIS AG (AT) 2013-10-30 EP disclosed
EP-2445963-B1 AUTOMOTIVE INTERIOR ARTICLE WITH REDUCED SMELL BOREALIS AG (AT) 2013-10-30 EP disclosed
US-20120123033-A1 POLYPROPYLENE MINERAL COMPOUND WITH REDUCED VOLATILES BOREALIS AG (AT) 2012-05-17 US disclosed
EP-2240542-B9 LOW-STICKY ADDITIVE PACKAGE FOR AUTOMOTIVE INTERIOR APPLICATIONS BOREALIS AG (AT) 2012-01-11 EP disclosed
EP-2240542-B1 LOW-STICKY ADDITIVE PACKAGE FOR AUTOMOTIVE INTERIOR APPLICATIONS BOREALIS AG (AT) 2011-06-15 EP disclosed
EP-1669426-B1 COATING COMPOSITION AND METHOD OF FORMING COATING FILM KANSAI PAINT CO LTD (JP) 2008-06-18 EP disclosed
EP-1669426-A1 COATING COMPOSITION AND METHOD OF FORMING COATING FILM KANSAI PAINT CO., LTD. (JP) 2006-06-14 EP disclosed
US-20050142297-A1 Coating compositions and method of forming coating film KANSAI PAINT CO., LTD. (JP) 2005-06-30 US disclosed