Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | SCD5 | Q86SK9 | 2/20 | 0.40 |
| ▸ | SCD | O00767 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11509425 | 0.89 | SCN3A (0.48) | HSD17B10OPRK1OPRM1MEN1KMT2A | |
| SCHEMBL11510688 | 0.89 | SCN3A (0.43) | HSD17B10OPRK1OPRM1MEN1KMT2A | |
| SCHEMBL11509550 | 0.88 | SCN3A (0.43) | HSD17B10OPRK1OPRM1MEN1KMT2A | |
| SCHEMBL24775507 | 0.84 | HSD17B10 (0.50) | HSD17B10MEN1KMT2ASCN3AALDH1A1 | |
| SCHEMBL11511652 | 0.78 | CHRNB2 (0.57) | HSD17B10OPRK1OPRM1 | |
| SCHEMBL11510005 | 0.77 | PARP14 (0.46) | SCN3AROCK2 | |
| SCHEMBL11509496 | 0.76 | OPRK1 (0.62) | HSD17B10OPRK1OPRM1MEN1KMT2A | |
| SCHEMBL11509465 | 0.74 | OPRK1 (0.58) | HSD17B10OPRK1OPRM1MEN1KMT2A | |
| SCHEMBL11512485 | 0.74 | OPRK1 (0.57) | HSD17B10OPRK1OPRM1MEN1KMT2A | |
| SCHEMBL8034151 | 0.73 | CHRNB2 (0.50) | MEN1KMT2ASCN3AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4161529-A | Phenoxy phenyl pyrrolidine compounds, compositions and methods of use | SCIENCE UNION ET CIE, SOCIETE FRANCAISE DE RECHERCHE MEDICALE (FR) | 1979-07-17 | — | — | US | disclosed |