Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 2/20 | 0.57 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.46 |
| ▸ | PDCD1LG2 | Q9BQ51 | 1/20 | 0.45 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | IL33 | O95760 | 2/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28519807 | 0.96 | OPRK1 (0.52) | OPRK1OPRM1MEN1KMT2AHSD17B10 | |
| SCHEMBL11510687 | 0.89 | OPRK1 (0.47) | OPRK1OPRM1MEN1KMT2AHRH3 | |
| SCHEMBL11509424 | 0.88 | CHRNB2 (0.46) | OPRK1OPRM1MEN1KMT2APDCD1LG2 | |
| SCHEMBL11509549 | 0.86 | LTA4H (0.48) | OPRK1OPRM1PDCD1LG2CD274FFAR1 | |
| SCHEMBL11509465 | 0.85 | OPRK1 (0.58) | OPRK1OPRM1MEN1KMT2AHSD17B10 | |
| SCHEMBL23507317 | 0.84 | DRD2 (0.57) | OPRK1OPRM1MEN1KMT2AHSD17B10 | |
| SCHEMBL11509496 | 0.83 | OPRK1 (0.62) | OPRK1OPRM1MEN1KMT2AHSD17B10 | |
| SCHEMBL28907187 | 0.82 | ALDH1A1 (0.45) | OPRK1OPRM1MEN1KMT2APDCD1LG2 | |
| SCHEMBL22639701 | 0.82 | OPRK1 (0.49) | OPRK1OPRM1MEN1KMT2AHSD17B10 | |
| SCHEMBL18306590 | 0.82 | OPRK1 (0.49) | OPRK1OPRM1MEN1KMT2AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4161529-A | Phenoxy phenyl pyrrolidine compounds, compositions and methods of use | SCIENCE UNION ET CIE, SOCIETE FRANCAISE DE RECHERCHE MEDICALE (FR) | 1979-07-17 | — | — | US | disclosed |