Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 2/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | IDO1 | P14902 | 1/20 | 0.45 |
| ▸ | MMP8 | P22894 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | METAP1 | P53582 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7323491 | 0.85 | METAP2 (0.60) | METAP2CYP2C19NPC1SMN1; SMN2RAB9A | |
| SCHEMBL2238552 | 0.85 | METAP2 (0.60) | METAP2CYP2C19NPC1SMN1; SMN2RAB9A | |
| Hydrochloric Acid SCHEMBL7323488 | 0.84 | METAP2 (0.59) | METAP2CYP2C19NPC1SMN1; SMN2RAB9A | |
| Hydrochloric Acid SCHEMBL3366424 | 0.84 | METAP2 (0.59) | METAP2CYP2C19NPC1SMN1; SMN2RAB9A | |
| SCHEMBL10683855 | 0.83 | LTA4H (0.50) | METAP2CYP2C19SMN1; SMN2IDO1ALDH1A1 | |
| SCHEMBL2829691 | 0.82 | CYP2C19 (0.61) | CYP2C19SMN1; SMN2IDO1ALDH1A1HPGD | |
| SCHEMBL341585 | 0.82 | CYP2C19 (0.61) | CYP2C19SMN1; SMN2IDO1ALDH1A1HPGD | |
| SCHEMBL2829688 | 0.82 | CYP2C19 (0.61) | CYP2C19SMN1; SMN2IDO1ALDH1A1HPGD | |
| SCHEMBL3712742 | 0.80 | SMN1; SMN2 (0.55) | METAP2SMN1; SMN2MMP8PIN1TDP1 | |
| SCHEMBL2635410 | 0.80 | SMN1; SMN2 (0.55) | METAP2SMN1; SMN2MMP8PIN1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4153729-A | ANTILIPEMIC AGENTS | RECHERCHES PHARMACEUTIQUES ET SCIENTIFIQUES (FR) | 1979-05-08 | — | — | US | disclosed |