SCHEMBL11512874

SCHEMBL11512874

C=CCOC(=O)NNS(=O)(=O)c1ccccc1

nearest known ligand 0.54

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
KAT6A Q92794 8/20 0.54
BCAT1 P54687 1/20 0.51
GAA P10253 3/20 0.48
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47
HTT P42858 2/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
CYP3A4 P08684 1/20 0.45
CASP1 P29466 1/20 0.44
ALDH1A1 P00352 1/20 0.44
MAPT P10636 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10668780 0.88 CYP3A4 (0.47) KAT6ASMN1; SMN2CYP3A4CASP1ALDH1A1
SCHEMBL13866362 0.82 ALDH1A1 (0.52) GAAKMT2ASMN1; SMN2ALDH1A1MAPT
SCHEMBL28463048 0.80 BCAT1 (0.60) KAT6ABCAT1GAAMEN1KMT2A
SCHEMBL11514436 0.79 BCAT1 (0.54) KAT6ABCAT1GAAMEN1KMT2A
SCHEMBL398042 0.77 PKM (0.52) GAAMEN1KMT2ASMN1; SMN2CYP3A4
SCHEMBL11513730 0.76 MEN1 (0.72) KAT6ABCAT1GAAMEN1KMT2A
SCHEMBL4557754 0.75 GAA (0.63) GAAMEN1KMT2ASMN1; SMN2CYP3A4
SCHEMBL11584614 0.74 BCAT1 (0.60) KAT6ABCAT1GAAMEN1KMT2A
SCHEMBL11851337 0.73 MEN1 (0.52) MEN1KMT2ASMN1; SMN2CYP3A4ALDH1A1
SCHEMBL11844069 0.73 NPSR1 (0.59) GAAMEN1KMT2ASMN1; SMN2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4135049-A SULFONYL CARBAZATES AS BLOWING AGENTS UNIROYAL, INC. (US) 1979-01-16 US disclosed
US-4012432-A Sulfonyl carbazates as blowing agents UNIROYAL INC. (US) 1977-03-15 US disclosed