Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 6/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.45 |
| ▸ | CASP1 | P29466 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL160077 | 0.83 | NPC1 (0.54) | CYP3A4TSHRSMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL11719915 | 0.78 | MEN1 (0.49) | GAACYP3A4TSHRSMN1; SMN2CASP1 | |
| SCHEMBL15721354 | 0.78 | LMNA (0.50) | GAACYP3A4TSHRSMN1; SMN2CASP1 | |
| SCHEMBL3463370 | 0.78 | CASP1 (0.52) | CYP3A4TSHRSMN1; SMN2CASP1ALDH1A1 | |
| SCHEMBL2234441 | 0.77 | GAA (1.00) | GAACYP3A4TSHRALOX5SMN1; SMN2 | |
| SCHEMBL4908338 | 0.77 | GAA (0.69) | GAATSHRSMN1; SMN2ALDH1A1KMT2A | |
| Hydrochloric Acid SCHEMBL28240039 | 0.76 | GAA (0.96) | GAACYP3A4TSHRALOX5SMN1; SMN2 | |
| SCHEMBL11694686 | 0.75 | EPHX1 (0.51) | GAACYP3A4SMN1; SMN2ALDH1A1HSD17B10 | |
| SCHEMBL11512874 | 0.75 | KAT6A (0.54) | GAACYP3A4SMN1; SMN2CASP1ALDH1A1 | |
| SCHEMBL10668780 | 0.74 | CYP3A4 (0.47) | CYP3A4TSHRSMN1; SMN2CASP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7592374-B2 | Insecticidal nitromethylene compounds | CROMPTON CORPORATION (US) | 2009-09-22 | — | — | US | disclosed |
| WO-2006094240-A1 | INSECTICIDAL, ACARICIDAL, AND FUNGICIDAL NITOMETHYLENE COMPOUNDS | CHEMTURA CORPORATION (US) | 2006-09-08 | — | — | WO | disclosed |
| US-20060199850-A1 | Insecticidal, acaricidal, and fungicidal nitromethylene compounds | WEBER CITY ROAD LLC | 2006-09-07 | — | — | US | disclosed |
| EP-1226106-A1 | PROCESS FOR THE PREPARATION OF INSECTICIDAL PHEYNYLHYDRAZINE DERIVATIVES | Crompton Corporation (US) | 2002-07-31 | — | — | EP | disclosed |
| US-6278022-B1 | REACTING SUBSTITUTED AROMATIC COMPOUND WITH NITRIC ACID TO FORM NITROAROMATIC COMPOUND; REDUCING NITRO GROUP OF AROMATIC COMPOUND TO FORM CORRESPONDING HYDROCHLORIDE SALT | CK WITCO CORPORATION | 2001-08-21 | — | — | US | disclosed |
| WO-2001032599-A1 | PROCESS FOR THE PREPARATION OF INSECTICIDAL PHEYNYLHYDRAZINE DERIVATIVES | CROMPTON CORPORATION (US) | 2001-05-10 | — | — | WO | disclosed |
| WO-2001032605-A1 | PROCESS FOR THE PREPARATION OF INSECTICIDAL PHENYLHYDRAZINE DERIVATIVES | CROMPTON CORPORATION (US) | 2001-05-10 | — | — | WO | disclosed |
| US-6166243-A | Process for the preparation of insecticidal phenylhydrazine derivatives | CK WITCO CORPORATION (US) | 2000-12-26 | — | — | US | disclosed |
| EP-0836596-B1 | HYDRAZINE DERIVATIVES | UNIROYAL CHEM CO INC (US) | 2000-08-23 | — | — | EP | disclosed |
| EP-0836596-A1 | HYDRAZINE DERIVATIVES | UNIROYAL CHEMICAL COMPANY, Inc. (US) | 1998-04-22 | — | — | EP | disclosed |
| WO-1997002275-A1 | PESTICIDAL PHENYLHYDRAZINE PHOSPHORUS DERIVATIVES | UNIROYAL CHEMICAL COMPANY, INC. (US) | 1997-01-23 | — | — | WO | disclosed |
| WO-1997002257-A1 | HYDRAZINE DERIVATIVES | UNIROYAL CHEMICAL COMPANY, INC. (US) | 1997-01-23 | — | — | WO | disclosed |
| EP-0641316-B1 | INSECTICIDAL PHENYLHYDRAZINE DERIVATIVES | UNIROYAL CHEM CO INC (US) | 1997-01-22 | — | — | EP | disclosed |
| US-5567723-A | Miticidal hydrazine compounds and their intermediates | UNIROYAL CHEMICAL COMPANY, INC. (US) | 1996-10-22 | — | — | US | disclosed |
| US-5543404-A | MITICIDES | UNIROYAL CHEMICAL COMPANY, INC (US) | 1996-08-06 | — | — | US | disclosed |
| US-5536746-A | Insecticidal phenylhydrazine derivatives | UNIROYAL CHEMICAL COMPANY, INC. (US) | 1996-07-16 | — | — | US | disclosed |
| US-5438123-A | Miticides, nematocides | UNIROYAL CHEMICAL COMPANY, INC. (US) | 1995-08-01 | — | — | US | disclosed |
| EP-0641316-A1 | INSECTICIDAL PHENYLHYDRAZINE DERIVATIVES. | UNIROYAL CHEM CO INC (US) | 1995-03-08 | — | — | EP | disclosed |
| US-5367093-A | Pesticides | UNIROYAL CHEMICAL COMPANY, INC. (US) | 1994-11-22 | — | — | US | disclosed |
| WO-1993010083-A1 | INSECTICIDAL PHENYLHYDRAZINE DERIVATIVES | UNIROYAL CHEMICAL COMPANY, INC. (US) | 1993-05-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060199850-A1 | Insecticidal, acaricidal, and fungicidal nitromethylene compounds | NIT2, DDT, AADAC | GAA 3908/4885CYP3A4 99/4885TSHR 2547/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.