Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | KMO | O15229 | 2/20 | 0.47 |
| ▸ | CTSS | P25774 | 1/20 | 0.45 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | AR | P10275 | 1/20 | 0.43 |
| ▸ | KDM1A | O60341 | 2/20 | 0.42 |
| ▸ | XDH | P47989 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.40 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.40 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11478689 | 0.77 | KDM4E (1.00) | KDM4EALDH1A1F2RL3LMNAKMO | |
| SCHEMBL9702278 | 0.73 | RAB9A (0.53) | KDM4EALDH1A1F2RL3TP53HPGD | |
| SCHEMBL23458469 | 0.72 | RAB9A (0.49) | KDM4EALDH1A1ARTP53CYP1A2 | |
| SCHEMBL9700913 | 0.72 | RAB9A (0.51) | KDM4EALDH1A1F2RL3TP53HPGD | |
| SCHEMBL1348540 | 0.70 | KDM4E (0.64) | KDM4EALDH1A1F2RL3LMNAKMO | |
| SCHEMBL11512880 | 0.70 | KDM4E (0.53) | KDM4EALDH1A1F2RL3LMNAKMO | |
| SCHEMBL22158562 | 0.70 | TLR8 (0.51) | KDM4EALDH1A1F2RL3LMNACTSS | |
| SCHEMBL17750392 | 0.70 | RAB9A (0.60) | KDM4EALDH1A1F2RL3LMNATP53 | |
| SCHEMBL9701997 | 0.70 | RAB9A (0.60) | KDM4EALDH1A1F2RL3LMNATP53 | |
| SCHEMBL2406368 | 0.70 | IDO1 (0.54) | KDM4EALDH1A1KMOCTSSIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992012154-A1 | IMIDAZOTRIAZINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-07-23 | — | — | WO | disclosed |