Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | TSHR | P16473 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | RECQL | P46063 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2379371 | 0.82 | TSHR (0.44) | CASP1ALDH1A1TSHRGAAPOLB | |
| SCHEMBL30987853 | 0.82 | TSHR (0.44) | CASP1ALDH1A1TSHRGAAPOLB | |
| SCHEMBL3356943 | 0.81 | CASP1 (0.44) | CASP1ALDH1A1TSHRGAAPOLB | |
| SCHEMBL9503147 | 0.80 | TSHR (0.43) | CASP1ALDH1A1TSHRGAAPOLB | |
| SCHEMBL9503076 | 0.79 | CASP1 (0.43) | CASP1ALDH1A1TSHRGAAPOLB | |
| SCHEMBL297275 | 0.78 | ALDH1A1 (0.59) | ALDH1A1TSHRGAAPOLBMAPT | |
| SCHEMBL12737452 | 0.78 | SMN1; SMN2 (0.54) | ALDH1A1TSHRPOLBMAPTNPC1 | |
| SCHEMBL14803471 | 0.78 | ALDH1A1 (0.54) | CASP1ALDH1A1TSHRGAAPOLB | |
| SCHEMBL11512947 | 0.78 | CASP1 (0.41) | CASP1ALDH1A1TSHRGAAPOLB | |
| SCHEMBL20869790 | 0.78 | CASP1 (0.41) | CASP1ALDH1A1TSHRGAAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 196 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4992527-A | Heat resistance, protective coatings, electronics | AMOCO CORPORATION (US) | 1991-02-12 | — | — | US | claimed |
| US-4973659-A | HEAR RESISTANT FILMS, FIBERS, COMPOSITES | AMOCO CORPORATION (US) | 1990-11-27 | — | — | US | claimed |
| US-4968780-A | SOLUBLE IN N-METHYLPYRROLIDONE, HIGH GLASS TRANSITION TEMPERATURE, HEAT RESISTANT FILMS, FIBERS AND COMPOSITES | AMOCO CORPORATION (US) | 1990-11-06 | — | — | US | claimed |
| CN-107501099-B | Modulators of ATP-binding cassette transporters | 沃泰克斯药物股份有限公司 | 2021-03-19 | — | — | CN | disclosed |
| EP-3705477-A1 | MODULATORS OF ATP-BINDING CASSETTE TRANSPORTERS | Vertex Pharmaceuticals Incorporated (US) | 2020-09-09 | — | — | EP | disclosed |
| EP-3705477-A1 | MODULATORS OF ATP-BINDING CASSETTE TRANSPORTERS | Vertex Pharmaceuticals Incorporated (US) | 2020-09-09 | — | — | EP | disclosed |
| US-10662192-B2 | Modulators of ATP-binding cassette transporters | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2020-05-26 | — | — | US | disclosed |
| US-10662192-B2 | Modulators of ATP-binding cassette transporters | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2020-05-26 | — | — | US | disclosed |
| EP-3216787-B1 | INTERMEDIATES FOR THE PREPARATION OF MODULATORS OF ATP-BINDING CASSETTE TRANSPORTERS | VERTEX PHARMA (US) | 2020-02-19 | — | — | EP | disclosed |
| EP-3216787-B1 | INTERMEDIATES FOR THE PREPARATION OF MODULATORS OF ATP-BINDING CASSETTE TRANSPORTERS | VERTEX PHARMA (US) | 2020-02-19 | — | — | EP | disclosed |
| US-20190144450-A1 | MODULATORS OF ATP-BINDING CASSETTE TRANSPORTERS | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2019-05-16 | — | — | US | disclosed |
| EP-0342943-A1 | Thermosetting resin composition | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1989-11-23 | — | — | EP | disclosed |
| EP-0178583-B1 | POLYURETHANE SYSTEMS USING MONOTERTIARY-ALKYLTOLUENEDIAMINE AS A CROSS LINKER | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1989-05-31 | — | — | EP | disclosed |
| EP-0311387-A2 | Aromatic amine resins, their production process and thermosetting resin compositions making use of the same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1989-04-12 | — | — | EP | disclosed |
| US-4816543-A | REACTIN INJECTION MOLDING MATERIALS | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1989-03-28 | — | — | US | disclosed |
| US-4745223-A | CHAIN EXTENDERS FOR POLYUREAS AND POLYURETHANES | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1988-05-17 | — | — | US | disclosed |
| EP-0178583-A1 | Polyurethane systems using monotertiary-alkyltoluenediamine as a cross linker | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1986-04-23 | — | — | EP | disclosed |
| EP-0177916-A1 | Mono-tertiary-alkylated toluenediamine and derivatives | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1986-04-16 | — | — | EP | disclosed |
| EP-0153606-A2 | Process for the production of polyurethane urea elastomers | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1985-09-04 | — | — | EP | disclosed |
| US-4482690-A | AROMATIC DIAMINE AS CHAIN EXTENDER | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1984-11-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190144450-A1 | MODULATORS OF ATP-BINDING CASSETTE TRANSPORTERS | CFTR, ABCB1, ABCC2 | CASP1 4480/4885ALDH1A1 2165/4885TSHR 2753/4885 |
| US-10662192-B2 | Modulators of ATP-binding cassette transporters | CFTR, ABCB1, ABCC2 | CASP1 4480/4885ALDH1A1 2165/4885TSHR 2753/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.