SCHEMBL11513121

SCHEMBL11513121

CCC(C)c1c(-c2ccccc2C(C)(C)C)cccc1C(C)(C)C

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 1/20 0.35
TSHR P16473 3/20 0.35
ALDH1A1 P00352 2/20 0.34
TDP1 Q9NUW8 1/20 0.34
CYP1A2 P05177 1/20 0.32
CYP3A4 P08684 1/20 0.32
CYP2C9 P11712 1/20 0.32
CYP2C19 P33261 1/20 0.32
GABRA1 P14867 1/20 0.32
GABRB2 P47870 1/20 0.32
TRPA1 O75762 1/20 0.31
KIF11 P52732 1/20 0.31
RORC P51449 2/20 0.30
PRKDC P78527 1/20 0.30
NPC1 O15118 1/20 0.30
MAPT P10636 1/20 0.30
NFKB1 P19838 1/20 0.30
RAB9A P51151 1/20 0.30
NFKB2 Q00653 1/20 0.30
RELA Q04206 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18419783 0.77 CA2 (0.36) CA2TSHRALDH1A1TDP1GABRA1
SCHEMBL24000896 0.77 CA2 (0.36) CA2TSHRALDH1A1TDP1CYP1A2
SCHEMBL1194484 0.74 ALDH1A1 (0.55) CA2TSHRALDH1A1TDP1CYP1A2
Phosphine SCHEMBL2238711 0.72 ALDH1A1 (0.52) CA2TSHRALDH1A1TDP1CYP1A2
SCHEMBL545684 0.72 ALDH1A1 (0.52) CA2TSHRALDH1A1TDP1CYP1A2
SCHEMBL24620116 0.72 TSHR (0.55) CA2TSHRALDH1A1TDP1CYP1A2
SCHEMBL27809376 0.70 CA2 (0.52) CA2TSHRALDH1A1TDP1CYP1A2
SCHEMBL11020611 0.70 ALDH1A1 (0.50) CA2TSHRALDH1A1TDP1CYP1A2
SCHEMBL8731742 0.69 TSHR (0.52) TSHRGABRA1GABRB2RORC
SCHEMBL11513127 0.68 TRPA1 (0.34) TSHRALDH1A1CYP1A2CYP3A4CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4177156-A SPECIALTY OILS FOR TRANSFORMERS RHONE-POULENC INDUSTRIES (FR) 1979-12-04 US disclosed
US-4119555-A COOLANTS FOR TRANSFORMERS RHONE-POULENC INDUSTRIES (FR) 1978-10-10 US disclosed