Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.41 |
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.37 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1194484 | 0.97 | ALDH1A1 (0.55) | ALDH1A1TDP1TSHRCA2TRPA1 | |
| Phosphine SCHEMBL2238711 | 0.94 | ALDH1A1 (0.52) | ALDH1A1TDP1TSHRCA2TRPA1 | |
| SCHEMBL11020611 | 0.92 | ALDH1A1 (0.50) | ALDH1A1TDP1TSHRCA2TRPA1 | |
| SCHEMBL24626773 | 0.85 | ALDH1A1 (0.44) | ALDH1A1TDP1TSHRCA2TRPA1 | |
| SCHEMBL20034068 | 0.85 | GABRA1 (0.50) | ALDH1A1TDP1TSHRCA2TRPA1 | |
| SCHEMBL5605717 | 0.83 | ALDH1A1 (0.43) | ALDH1A1TDP1TSHRCA2TRPA1 | |
| SCHEMBL2682153 | 0.83 | CA2 (0.44) | ALDH1A1TDP1TSHRCA2TRPA1 | |
| SCHEMBL9261398 | 0.83 | CYP2A6 (0.44) | ALDH1A1TDP1TSHRCA2TRPA1 | |
| SCHEMBL21798723 | 0.83 | ALDH1A1 (0.43) | ALDH1A1TDP1TSHRCA2TRPA1 | |
| SCHEMBL23105552 | 0.83 | ALDH1A1 (0.59) | ALDH1A1TDP1TSHRCA2TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12421178-B2 | Non-cryogenic, ammonia-free reduction of aryl compounds | University of Pittsburgh—of the Commonwealth System of Higher Education (US) | 2025-09-23 | — | — | US | disclosed |
| US-20240092708-A1 | Non-Cryogenic, Ammonia-Free Reduction of Aryl Compounds | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION | 2024-03-21 | — | — | US | disclosed |
| US-11866386-B2 | Non-cryogenic, ammonia-free reduction of aryl compounds | University of Pittsburgh—of the Commonwealth System of Higher Education (US) | 2024-01-09 | — | — | US | disclosed |
| US-20220089508-A1 | Non-Cryogenic, Ammonia-Free Reduction of Aryl Compounds | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION | 2022-03-24 | — | — | US | disclosed |
| EP-3052513-B1 | INDUSTRIAL PROCESS FOR THE SYNTHESIS OF ULIPRISTAL ACETATE AND ITS 4'-ACETYL ANALOGUE | RICHTER GEDEON NYRT (HU) | 2018-12-05 | — | — | EP | disclosed |
| EP-3004036-B1 | METHODS OF SYNTHESIS OF INGENOL AND INTERMEDIATES THEREOF | LEO LABORATORIES LTD (IE) | 2017-11-22 | — | — | EP | disclosed |
| US-9676814-B2 | Industrial process for the synthesis of ulipristal acetate and its 4′-acetyl analogue | RICHTER GEDEON NYRT. (HU) | 2017-06-13 | — | — | US | disclosed |
| US-20160311849-A1 | Industrial Process for the Synthesis of Ulipristal Acetate and its 4'-Acetyl Analogue | RICHTER GEDEON NYRT. (HU) | 2016-10-27 | — | — | US | disclosed |
| EP-3052513-A1 | INDUSTRIAL PROCESS FOR THE SYNTHESIS OF ULIPRISTAL ACETATE AND ITS 4'-ACETYL ANALOGUE | Richter Gedeon Nyrt. (HU) | 2016-08-10 | — | — | EP | disclosed |
| US-20160107977-A1 | METHODS OF SYNTHESIS OF INGENOL AND INTERMEDIATES THEREOF | LEO LABORATORIES LIMITED (IE) | 2016-04-21 | — | — | US | disclosed |
| US-5281585-A | Secondary amide containing antagonist | MERCK & CO., INC. (US) | 1994-01-25 | — | — | US | disclosed |
| WO-1993003071-A1 | PREPARATION OF FUNCTIONALIZED POLYMERS UTILIZING A REACTIVE FORM OF CALCIUM | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA (US) | 1993-02-18 | — | — | WO | disclosed |
| WO-1992019595-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 1992-11-12 | — | — | WO | disclosed |
| EP-0512831-A1 | Fibrinogen receptor antagonists | MERCK & CO. INC. (US) | 1992-11-11 | — | — | EP | disclosed |
| EP-0268400-B1 | STEROIDAL 17ALPHA-SILYL ETHERS AND PROCESS TO CORTICOIDS AND PROGESTERONES | THE UPJOHN COMPANY (US) | 1992-04-29 | — | — | EP | disclosed |
| US-4977255-A | Steroidal 17α-silyl ethers and process to corticoids and progesterones | THE UPJOHN COMPANY (US) | 1990-12-11 | — | — | US | disclosed |
| US-4921638-A | 17β-cyano-9α,17α-dihydroxyandrost-4-en-3-one | THE UPJOHN COMPANY (US) | 1990-05-01 | — | — | US | disclosed |
| EP-0334875-A1 | STEROIDAL 17$g(a)-SILYL ETHERS AND PROCESS TO CORTICOIDS AND PROGGESTERONES | THE UPJOHN COMPANY (US) | 1989-10-04 | — | — | EP | disclosed |
| EP-0268400-A1 | Steroidal 17alpha-silyl ethers and process to corticoids and progesterones | THE UPJOHN COMPANY (US) | 1988-05-25 | — | — | EP | disclosed |
| WO-1988003534-A1 | STEROIDAL 17alpha-SILYL ETHERS AND PROCESS TO CORTICOIDS AND PROGGESTERONES | THE UPJOHN COMPANY (US) | 1988-05-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240092708-A1 | Non-Cryogenic, Ammonia-Free Reduction of Aryl Compounds | NAT1, AADAC, ARNT | ALDH1A1 3341/4885TDP1 2066/4885TSHR 3203/4885 |
| US-20160311849-A1 | Industrial Process for the Synthesis of Ulipristal Acetate and its 4'-Acetyl Analogue | AADAC, NAT1, UBA1 | ALDH1A1 26/4885TDP1 3697/4885TSHR 3308/4885 |
| US-12421178-B2 | Non-cryogenic, ammonia-free reduction of aryl compounds | NAT1, AADAC, ARNT | ALDH1A1 3341/4885TDP1 2066/4885TSHR 3203/4885 |
| US-20160107977-A1 | METHODS OF SYNTHESIS OF INGENOL AND INTERMEDIATES THEREOF | CYP51A1, ERG28, UTP20 | ALDH1A1 2734/4885TDP1 4649/4885TSHR 2376/4885 |
| US-20220089508-A1 | Non-Cryogenic, Ammonia-Free Reduction of Aryl Compounds | NAT1, AADAC, ARNT | ALDH1A1 3341/4885TDP1 2066/4885TSHR 3203/4885 |
| US-11866386-B2 | Non-cryogenic, ammonia-free reduction of aryl compounds | NAT1, AADAC, ARNT | ALDH1A1 3341/4885TDP1 2066/4885TSHR 3203/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.