SCHEMBL11513320

SCHEMBL11513320

CCOC(=O)N(NC(N)=O)S(=O)(=O)c1ccccc1

nearest known ligand 0.49

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
PTGES O14684 1/20 0.42
KMT2A Q03164 3/20 0.42
TSHR P16473 1/20 0.42
ATM Q13315 1/20 0.41
ALDH1A1 P00352 5/20 0.41
LMNA P02545 3/20 0.41
MEN1 O00255 2/20 0.40
GAA P10253 1/20 0.40
HPGD P15428 1/20 0.40
MAPT P10636 1/20 0.40
POLB P06746 2/20 0.40
MAPK1 P28482 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
CA12 O43570 1/20 0.39
CA9 Q16790 1/20 0.39
HSD17B10 Q99714 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
TP53 P04637 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11513073 0.87 ATM (0.48) PTGESKMT2ATSHRATMALDH1A1
SCHEMBL11515768 0.85 PTGES (0.43) PTGESKMT2AALDH1A1MEN1MAPK1
SCHEMBL11513014 0.85 PTGES (0.41) PTGESKMT2ATSHRATMALDH1A1
SCHEMBL11514144 0.81 F2 (0.41) PTGESKMT2ATSHRPOLBMAPK1
SCHEMBL11513322 0.81 ATM (0.47) PTGESKMT2ATSHRATMALDH1A1
SCHEMBL11513450 0.79 APOBEC3G (0.42) PTGESKMT2ATSHRMEN1SMN1; SMN2
SCHEMBL11511800 0.78 KMT2A (0.45) KMT2ATSHRATMALDH1A1LMNA
SCHEMBL11853584 0.76 HSD11B1 (0.56) KMT2ATSHRATMALDH1A1LMNA
SCHEMBL8762201 0.76 PTGES (0.73) PTGESKMT2AALDH1A1LMNAMEN1
SCHEMBL30309104 0.75 POLB (0.47) KMT2ATSHRATMALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4175200-A N,N-Disubstituted sulfonyl hydrazines UNIROYAL, INC. (US) 1979-11-20 US disclosed