Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11513073 | 0.87 | ATM (0.48) | ATMALDH1A1HPGDGAAKMT2A | |
| SCHEMBL11515773 | 0.85 | ALDH1A1 (0.43) | ALDH1A1GAAKMT2AMAPTSMN1; SMN2 | |
| SCHEMBL11513009 | 0.85 | ATM (0.46) | ATMALDH1A1HPGDGAAKMT2A | |
| SCHEMBL11513320 | 0.81 | PTGES (0.42) | ATMALDH1A1HPGDGAAKMT2A | |
| SCHEMBL11513450 | 0.79 | APOBEC3G (0.42) | KMT2AMEN1TSHRSMN1; SMN2CA12 | |
| SCHEMBL27452990 | 0.77 | CA1 (0.44) | KMT2ATSHRSMN1; SMN2CA12CA1 | |
| SCHEMBL11513014 | 0.74 | PTGES (0.41) | ATMALDH1A1HPGDGAAKMT2A | |
| SCHEMBL8645410 | 0.74 | APOBEC3G (0.44) | KMT2ATSHRSMN1; SMN2CA12CA1 | |
| SCHEMBL17728318 | 0.74 | ALDH1A1 (0.50) | ALDH1A1HPGDGAAKMT2AMEN1 | |
| SCHEMBL8611691 | 0.73 | HSD11B1 (0.40) | KMT2AMAPTTSHRCYP2C19SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4175200-A | N,N-Disubstituted sulfonyl hydrazines | UNIROYAL, INC. (US) | 1979-11-20 | — | — | US | disclosed |