SCHEMBL11515768

SCHEMBL11515768

COC(=O)N(NC(N)=O)S(=O)(=O)c1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
PTGES O14684 3/20 0.43
KMT2A Q03164 2/20 0.41
HSD11B1 P28845 1/20 0.41
MAPK1 P28482 2/20 0.40
ALDH1A1 P00352 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.39
NR1I2 O75469 1/20 0.39
RAB9A P51151 1/20 0.39
MEN1 O00255 1/20 0.38
APOBEC3G Q9HC16 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11512832 0.86 ALDH1A1 (0.44) PTGESKMT2AHSD11B1MAPK1ALDH1A1
SCHEMBL11513320 0.85 PTGES (0.42) PTGESKMT2AMAPK1ALDH1A1L3MBTL1
SCHEMBL11514144 0.85 F2 (0.41) PTGESKMT2AHSD11B1MAPK1
SCHEMBL11513450 0.83 APOBEC3G (0.42) PTGESKMT2AHSD11B1MEN1APOBEC3G
SCHEMBL11515773 0.78 ALDH1A1 (0.43) PTGESKMT2AHSD11B1MAPK1ALDH1A1
SCHEMBL28252160 0.77 HSD11B1 (0.50) KMT2AHSD11B1MAPK1ALDH1A1NR1I2
SCHEMBL14126507 0.76 APOBEC3G (0.45) KMT2AHSD11B1MEN1APOBEC3G
SCHEMBL1670976 0.76 APOBEC3G (0.41) KMT2AHSD11B1MAPK1ALDH1A1MEN1
SCHEMBL27452990 0.75 CA1 (0.44) PTGESKMT2AHSD11B1APOBEC3G
SCHEMBL11512464 0.74 PTGES (0.45) PTGESKMT2AALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4175200-A N,N-Disubstituted sulfonyl hydrazines UNIROYAL, INC. (US) 1979-11-20 US disclosed