Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | TNFRSF1A | P19438 | 2/20 | 0.33 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.33 |
| ▸ | FEN1 | P39748 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29113869 | 0.89 | PTGS2 (0.46) | DHFRPTGS2TSHRALDH1A1TDP1 | |
| SCHEMBL12706039 | 0.82 | RARG (0.39) | DHFRPTGS2TSHRALDH1A1TDP1 | |
| SCHEMBL1530338 | 0.80 | CA2 (0.41) | DHFRPTGS2TSHRALDH1A1TDP1 | |
| SCHEMBL482603 | 0.80 | DHFR (0.37) | DHFRPTGS2TSHRALDH1A1TDP1 | |
| SCHEMBL699612 | 0.80 | DHFR (0.37) | DHFRPTGS2TSHRALDH1A1TDP1 | |
| SCHEMBL1730807 | 0.80 | PTGS2 (0.40) | DHFRPTGS2TSHRALDH1A1TDP1 | |
| SCHEMBL16608098 | 0.79 | ALDH1A1 (0.38) | TSHRALDH1A1TDP1PTGS1CYP3A4 | |
| SCHEMBL11514753 | 0.79 | KMT2A (0.39) | DHFRPTGS2TSHRALDH1A1TDP1 | |
| SCHEMBL29113874 | 0.78 | ALDH1A1 (0.35) | DHFRPTGS2TSHRALDH1A1TDP1 | |
| SCHEMBL1731694 | 0.77 | DHFR (0.38) | DHFRPTGS2TSHRALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4171203-A | IN COMBINATION WITH A TETRAAMINOPYRIMIDING COUPLER SURFACTANTS AND THICKENERS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1979-10-16 | — | — | US | disclosed |