SCHEMBL11513709

SCHEMBL11513709

Cc1cc(C)c(C(S)S)cc1C

nearest known ligand 0.35

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.35
TSHR P16473 1/20 0.35
MAPK1 P28482 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26939188 0.80 CYP3A4 (0.33) CYP3A4TSHRMAPK1
SCHEMBL10436723 0.73 CYP3A4 (0.36) CYP3A4TSHRMAPK1
SCHEMBL4972071 0.73 LMNA (0.39) CYP3A4TSHRMAPK1
SCHEMBL754453 0.71 CYP3A4 (0.41) CYP3A4TSHRMAPK1
SCHEMBL10770592 0.71 CYP3A4 (0.35) CYP3A4TSHRMAPK1
SCHEMBL8437079 0.71 CYP3A4 (0.35) CYP3A4TSHRMAPK1
SCHEMBL3024230 0.70 CYP3A4 (0.31) CYP3A4TSHRMAPK1
SCHEMBL27985115 0.69 CYP3A4 (0.46) CYP3A4TSHRMAPK1
SCHEMBL8109982 0.69 TSHR (0.57) CYP3A4TSHRMAPK1
SCHEMBL12471360 0.69 CYP3A4 (0.39) CYP3A4TSHRMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4136086-A MERCAPTO-GLYCIDYL ADDUCT CIBA-GEIGY CORPORATION (US) 1979-01-23 US disclosed