Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.32 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | CASR | P41180 | 1/20 | 0.31 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL115072 | 0.86 | KDM4E (0.36) | SMN1; SMN2TP53KDM4EALDH1A1HPGD | |
| SCHEMBL116023 | 0.82 | METAP2 (0.40) | ESR1ESR2 | |
| SCHEMBL113677 | 0.82 | KCNA3 (0.32) | TP53KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL116066 | 0.81 | KCNA3 (0.40) | SMN1; SMN2LMNATP53KDM4EALDH1A1 | |
| SCHEMBL115060 | 0.81 | KDM4E (0.37) | SMN1; SMN2LMNARAB9ATP53KDM4E | |
| SCHEMBL114950 | 0.79 | SMN1; SMN2 (0.34) | SMN1; SMN2LMNARAB9ATP53KDM4E | |
| SCHEMBL114962 | 0.78 | SMN1; SMN2 (0.34) | SMN1; SMN2LMNARAB9ATP53KDM4E | |
| SCHEMBL116012 | 0.76 | ADORA3 (0.36) | SMN1; SMN2LMNARAB9ATP53KDM4E | |
| SCHEMBL115355 | 0.76 | SMN1; SMN2 (0.34) | SMN1; SMN2LMNARAB9ATP53KDM4E | |
| SCHEMBL113626 | 0.73 | SMN1; SMN2 (0.34) | SMN1; SMN2LMNARAB9ATP53ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120058893-A1 | HERBICIDALLY ACTIVE KETOSULTAMS AND DIKETOPYRIDINES | BAYER CROPSCIENCE AG (DE) | 2012-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120058893-A1 | HERBICIDALLY ACTIVE KETOSULTAMS AND DIKETOPYRIDINES | KHK, KCNA1, KCNA2 | SMN1; SMN2 4450/4885LMNA 3651/4885RAB9A 3859/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.