Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 9/20 | 0.46 |
| ▸ | CA2 | P00918 | 9/20 | 0.46 |
| ▸ | CA9 | Q16790 | 9/20 | 0.46 |
| ▸ | CA12 | O43570 | 8/20 | 0.46 |
| ▸ | MMP12 | P39900 | 2/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 5/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11515374 | 1.00 | LMNA (0.48) | LMNAKMT2APOLBALDH1A1CA1 | |
| SCHEMBL16393029 | 0.88 | LMNA (0.49) | LMNAKMT2APOLBALDH1A1CA1 | |
| SCHEMBL16392904 | 0.86 | LMNA (0.51) | LMNAKMT2APOLBALDH1A1CA1 | |
| SCHEMBL16393023 | 0.82 | LMNA (0.44) | LMNAKMT2APOLBALDH1A1CA1 | |
| SCHEMBL22559700 | 0.81 | LMNA (0.55) | LMNAKMT2APOLBALDH1A1CA1 | |
| SCHEMBL21133688 | 0.78 | LMNA (0.50) | LMNAKMT2APOLBALDH1A1CA1 | |
| Hydrochloric Acid SCHEMBL5741360 | 0.78 | LMNA (0.50) | LMNAKMT2APOLBALDH1A1CA1 | |
| SCHEMBL11516889 | 0.78 | LMNA (0.44) | LMNAKMT2APOLBALDH1A1CA1 | |
| SCHEMBL24834124 | 0.77 | LMNA (0.56) | LMNAKMT2APOLBALDH1A1CA1 | |
| SCHEMBL6232438 | 0.77 | LMNA (0.56) | LMNAKMT2APOLBALDH1A1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4157439-A | ANTITUMOR, LOW TOXICITY, NONHYDROLYZING | SUAMI T (JP) | 1979-06-05 | — | — | US | disclosed |