Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | MMP12 | P39900 | 2/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 7/20 | 0.43 |
| ▸ | CA2 | P00918 | 7/20 | 0.43 |
| ▸ | CA9 | Q16790 | 7/20 | 0.43 |
| ▸ | CA12 | O43570 | 6/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11516890 | 1.00 | LMNA (0.44) | LMNAKMT2AALDH1A1POLBMMP12 | |
| SCHEMBL11507787 | 0.90 | CA12 (0.51) | ALDH1A1MMP12MMP9CA1CA2 | |
| SCHEMBL11507566 | 0.90 | CA12 (0.51) | ALDH1A1MMP12MMP9CA1CA2 | |
| SCHEMBL29737839 | 0.86 | LMNA (0.52) | LMNAKMT2AALDH1A1POLBCA1 | |
| SCHEMBL11510647 | 0.80 | CA12 (0.52) | MMP12MMP9CA1CA2CA9 | |
| SCHEMBL16392904 | 0.80 | LMNA (0.51) | LMNAKMT2AALDH1A1POLBMMP12 | |
| SCHEMBL11507781 | 0.79 | ADRA2A (0.43) | LMNAKMT2AALDH1A1MMP12MMP9 | |
| SCHEMBL11507523 | 0.78 | CA12 (0.50) | MMP12MMP9CA1CA2CA9 | |
| SCHEMBL11515374 | 0.78 | LMNA (0.48) | LMNAKMT2AALDH1A1POLBMMP12 | |
| SCHEMBL11515380 | 0.78 | LMNA (0.48) | LMNAKMT2AALDH1A1POLBMMP12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4157439-A | ANTITUMOR, LOW TOXICITY, NONHYDROLYZING | SUAMI T (JP) | 1979-06-05 | — | — | US | claimed |
| US-4157439-A | ANTITUMOR, LOW TOXICITY, NONHYDROLYZING | SUAMI T (JP) | 1979-06-05 | — | — | US | disclosed |