Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 10/20 | 0.40 |
| ▸ | PGR | P06401 | 4/20 | 0.35 |
| ▸ | NR3C1 | P04150 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11517544 | 0.78 | PGR (0.41) | CYP19A1PGRNR3C1TDP1LMNA | |
| SCHEMBL11515543 | 0.78 | CYP19A1 (0.33) | CYP19A1PGRNR3C1LMNANR1I2 | |
| SCHEMBL11516228 | 0.76 | PGR (0.38) | CYP19A1PGRNR3C1TDP1LMNA | |
| SCHEMBL11519477 | 0.76 | PGR (0.38) | CYP19A1PGRNR3C1TDP1LMNA | |
| SCHEMBL11745870 | 0.74 | CYP19A1 (0.34) | CYP19A1PGRNR3C1LMNAOR51E2 | |
| SCHEMBL11745879 | 0.74 | CYP19A1 (0.34) | CYP19A1PGRNR3C1LMNAOR51E2 | |
| SCHEMBL11746471 | 0.69 | PGR (0.51) | CYP19A1PGRNR3C1TDP1LMNA | |
| SCHEMBL11518319 | 0.69 | NR3C1 (0.38) | CYP19A1PGRNR3C1TDP1LMNA | |
| SCHEMBL11517978 | 0.67 | CYP19A1 (0.34) | CYP19A1PGRNR3C1TDP1LMNA | |
| SCHEMBL11517777 | 0.67 | CYP19A1 (0.34) | CYP19A1PGRNR3C1TDP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4134891-A | 14-Functionalized 8,19-oxido steroids and processes for preparation thereof | STEELE CHEMICALS CO. LTD. (CA) | 1979-01-16 | — | — | US | disclosed |