Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.30 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.30 |
| ▸ | PGR | P06401 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11515538 | 0.78 | CYP19A1 (0.40) | CYP19A1LMNANR1I2NR3C1PGR | |
| SCHEMBL11516233 | 0.76 | TDP1 (0.31) | LMNANR3C1PGR | |
| SCHEMBL11745870 | 0.71 | CYP19A1 (0.34) | CYP19A1LMNANR1I2NR3C1PGR | |
| SCHEMBL11745879 | 0.71 | CYP19A1 (0.34) | CYP19A1LMNANR1I2NR3C1PGR | |
| SCHEMBL11744273 | 0.70 | LMNA (0.35) | CYP19A1LMNANR1I2NR3C1PGR | |
| SCHEMBL11745349 | 0.70 | LMNA (0.35) | CYP19A1LMNANR1I2NR3C1PGR | |
| SCHEMBL11744287 | 0.70 | LMNA (0.35) | CYP19A1LMNANR1I2NR3C1PGR | |
| SCHEMBL11517782 | 0.67 | — | — | |
| SCHEMBL11649963 | 0.64 | — | — | |
| SCHEMBL11517544 | 0.61 | PGR (0.41) | CYP19A1LMNANR1I2NR3C1PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4134891-A | 14-Functionalized 8,19-oxido steroids and processes for preparation thereof | STEELE CHEMICALS CO. LTD. (CA) | 1979-01-16 | — | — | US | disclosed |