Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 4/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.51 |
| ▸ | AR | P10275 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.51 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.51 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.51 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 8/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | NR3C1 | P04150 | 3/20 | 0.44 |
| ▸ | NR1I2 | O75469 | 3/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11741906 | 0.84 | PGR (0.48) | PGRCYP3A4CYP2C19ARALDH1A1 | |
| SCHEMBL11741911 | 0.84 | PGR (0.48) | PGRCYP3A4CYP2C19ARALDH1A1 | |
| SCHEMBL11226298 | 0.84 | LMNA (0.61) | PGRCYP3A4CYP2C19ARALDH1A1 | |
| SCHEMBL13178827 | 0.82 | CYP17A1 (0.62) | PGRCYP3A4CYP2C19ARALDH1A1 | |
| SCHEMBL11429970 | 0.81 | CYP19A1 (0.57) | PGRCYP3A4CYP2C19ARALDH1A1 | |
| SCHEMBL12101447 | 0.80 | CYP17A1 (0.60) | PGRCYP3A4CYP2C19ARALDH1A1 | |
| SCHEMBL1221844 | 0.80 | CYP17A1 (0.60) | PGRCYP3A4CYP2C19ARALDH1A1 | |
| SCHEMBL11517544 | 0.80 | PGR (0.41) | PGRCYP3A4CYP2C19ARALDH1A1 | |
| SCHEMBL11104875 | 0.80 | ALDH1A1 (0.63) | PGRCYP3A4CYP2C19ARALDH1A1 | |
| SCHEMBL11104861 | 0.80 | ALDH1A1 (0.63) | PGRCYP3A4CYP2C19ARALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4058539-A | 4,6,8(14)-Triene steroids | STEELE CHEMICALS CO. LTD. (CA) | 1977-11-15 | — | — | US | disclosed |