Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11517782 | 0.90 | — | — | |
| SCHEMBL11649963 | 0.88 | — | — | |
| SCHEMBL11516228 | 0.78 | PGR (0.38) | TDP1LMNANR3C1PGRPDE4D | |
| SCHEMBL11519477 | 0.78 | PGR (0.38) | TDP1LMNANR3C1PGRPDE4D | |
| SCHEMBL11649488 | 0.78 | — | — | |
| SCHEMBL11515543 | 0.76 | CYP19A1 (0.33) | LMNANR3C1PGR | |
| SCHEMBL11516496 | 0.72 | LMNA (0.33) | LMNANR3C1PGR | |
| SCHEMBL11516494 | 0.72 | LMNA (0.33) | LMNANR3C1PGR | |
| SCHEMBL11741911 | 0.71 | PGR (0.48) | TDP1LMNANR3C1PGRPDE4D | |
| SCHEMBL11741906 | 0.71 | PGR (0.48) | TDP1LMNANR3C1PGRPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4134891-A | 14-Functionalized 8,19-oxido steroids and processes for preparation thereof | STEELE CHEMICALS CO. LTD. (CA) | 1979-01-16 | — | — | US | disclosed |
| US-4102883-A | 19,8-Lactone steroid derivatives and processes of preparation thereof | STEELE CHEMICALS CO. LTD. (CA) | 1978-07-25 | — | — | US | disclosed |
| US-4096142-A | 14,19-Dioxygenated steroid compounds and their 14-dehydro analogs and process for the preparation thereof | STEELE CHEMICALS CO. LTD. (CA) | 1978-06-20 | — | — | US | disclosed |