SCHEMBL11516136

SCHEMBL11516136

[c]1ccc(-c2cnc(-c3cc[c]cc3)o2)cc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.62
ALOX15 P16050 1/20 0.62
CASP1 P29466 1/20 0.62
RAB9A P51151 9/20 0.53
MEN1 O00255 4/20 0.53
KMT2A Q03164 4/20 0.53
MITF O75030 1/20 0.53
NPC1 O15118 8/20 0.51
KDM4E B2RXH2 7/20 0.51
ALDH1A1 P00352 7/20 0.51
HPGD P15428 7/20 0.51
HSD17B10 Q99714 5/20 0.51
SMN1; SMN2 Q16637 5/20 0.51
TP53 P04637 3/20 0.51
GAA P10253 3/20 0.51
STAT1 P42224 1/20 0.51
CYP1A2 P05177 2/20 0.46
CYP2C9 P11712 2/20 0.46
CYP2C19 P33261 2/20 0.46
CASP3 P42574 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10810422 0.93 ALOX15 (0.76) TSHRALOX15CASP1RAB9AMEN1
SCHEMBL28198257 0.93 ALOX15 (0.76) TSHRALOX15CASP1RAB9AMEN1
SCHEMBL620114 0.85 ALOX15 (0.51) TSHRALOX15CASP1RAB9AMEN1
SCHEMBL74359 0.78 ALOX15 (0.96) TSHRALOX15CASP1RAB9AMEN1
SCHEMBL1770347 0.78 CA12 (0.53) TSHRALOX15CASP1RAB9AMEN1
SCHEMBL75219 0.77 ALOX15 (1.00) TSHRALOX15CASP1RAB9AMEN1
SCHEMBL10726923 0.77 ALOX15 (1.00) TSHRALOX15CASP1RAB9AMEN1
SCHEMBL17696815 0.75 RAB9A (0.86) TSHRALOX15CASP1RAB9AMEN1
SCHEMBL1179970 0.75 HSD17B1 (0.72) TSHRALOX15CASP1RAB9AMEN1
SCHEMBL14947177 0.75 RAB9A (0.83) TSHRALOX15CASP1RAB9AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4164480-A POLYMER STABILIZERS EASTMAN KODAK COMPANY (US) 1979-08-14 US disclosed
US-4105631-A MULTICHROMOPHORIC ULTRAVIOLET STABILIZERS AND THEIR USE IN ORGANIC COMPOSITIONS EASTMAN KODAK COMPANY (US) 1978-08-08 US disclosed
US-4043973-A PIGMENTS, COLORANTS, FILLERS, REINFORCING AGENTS EASTMAN KODAK COMPANY (US) 1977-08-23 US disclosed
US-3939115-A OXADIAZOLES EASTMAN KODAK COMPANY (US) 1976-02-17 US disclosed
US-3936419-A Multichromophoric ultraviolet stabilizers and their use in organic compositions EASTMAN KODAK COMPANY (US) 1976-02-03 US disclosed