Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.46 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 5/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | NQO1 | P15559 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9031549 | 0.83 | LMNA (0.53) | MAPTALDH1A1KDM4ETDP1POLB | |
| Iodide SCHEMBL6660089 | 0.82 | MAPT (0.43) | MAPTALDH1A1KDM4ETDP1POLB | |
| SCHEMBL13652077 | 0.81 | MAPT (0.73) | MAPTALDH1A1KDM4ETDP1POLB | |
| Hydrochloric Acid SCHEMBL11516850 | 0.74 | INSR (0.50) | MAPTALDH1A1KDM4ETDP1POLB | |
| SCHEMBL19305186 | 0.74 | APP (0.64) | ALDH1A1POLBPSMB8KMT2AHSD17B10 | |
| Hydrochloric Acid SCHEMBL39077 | 0.73 | APP (0.65) | ALDH1A1POLBPSMB8KMT2AHSD17B10 | |
| SCHEMBL17835477 | 0.73 | SNCA (0.50) | MAPTALDH1A1POLBPSMB8KMT2A | |
| SCHEMBL11516326 | 0.70 | MAPT (0.45) | MAPTALDH1A1KDM4ETDP1POLB | |
| Iodide SCHEMBL11599406 | 0.69 | MAPT (0.62) | MAPTALDH1A1KDM4ETDP1POLB | |
| SCHEMBL6658511 | 0.68 | KDM4E (0.42) | MAPTALDH1A1KDM4ETDP1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4145537-A | BENZOTHIAZOLIUM DYES | BAYER AKTIENGESELLSCHAFT (DE) | 1979-03-20 | — | — | US | disclosed |