Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11516370 | 0.82 | MAPT (0.50) | MAPTPOLBPSMB8ALDH1A1KMT2A | |
| SCHEMBL9031549 | 0.78 | LMNA (0.53) | MAPTPOLBPSMB8ALDH1A1KMT2A | |
| Iodide SCHEMBL6663647 | 0.74 | SMN1; SMN2 (0.38) | MAPTPOLBALDH1A1KMT2ATSHR | |
| SCHEMBL30924937 | 0.72 | ALDH1A1 (0.33) | MAPTPOLBALDH1A1KMT2AMEN1 | |
| SCHEMBL22190283 | 0.71 | MAPT (0.40) | MAPTPOLBPSMB8ALDH1A1KMT2A | |
| Iodide SCHEMBL7335651 | 0.71 | MAPT (0.47) | MAPTPOLBALDH1A1KMT2AHSD17B10 | |
| SCHEMBL12301906 | 0.70 | PIK3CA (0.37) | MAPTPOLBALDH1A1KMT2AHSD17B10 | |
| SCHEMBL13652085 | 0.70 | MAPT (0.67) | MAPTPOLBPSMB8ALDH1A1KMT2A | |
| Hydrochloric Acid SCHEMBL11516847 | 0.69 | INSR (0.50) | MAPTPOLBPSMB8ALDH1A1KMT2A | |
| SCHEMBL19305186 | 0.69 | APP (0.64) | POLBPSMB8ALDH1A1KMT2AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004010761-A2 | PESTICIDAL CYANINE DYE DERIVATIVES | FMC CORPORATION (US) | 2004-02-05 | — | — | WO | disclosed |