Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 9/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 4/20 | 0.35 |
| ▸ | HEXA | P06865 | 1/20 | 0.33 |
| ▸ | HEXB | P07686 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | LCK | P06239 | 1/20 | 0.32 |
| ▸ | YES1 | P07947 | 1/20 | 0.32 |
| ▸ | SRC | P12931 | 1/20 | 0.32 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL115161 | 0.92 | HEXA (0.36) | CASRNR1I2HEXAHEXBABL1 | |
| SCHEMBL113787 | 0.89 | PDE4B (0.36) | CASRNR1I2HEXAHEXBALDH1A1 | |
| SCHEMBL115144 | 0.86 | CASR (0.38) | CASRNR1I2HEXAHEXB | |
| SCHEMBL115354 | 0.84 | ALDH1A1 (0.37) | CASRNR1I2HEXAHEXBALDH1A1 | |
| SCHEMBL115332 | 0.84 | TLR8 (0.35) | CASRHEXAHEXBALDH1A1ABL1 | |
| SCHEMBL115292 | 0.84 | CASR (0.36) | CASRNR1I2 | |
| SCHEMBL113811 | 0.83 | CASR (0.35) | CASRNR1I2ALDH1A1MEN1KMT2A | |
| SCHEMBL115168 | 0.83 | CASR (0.34) | CASRNR1I2MEN1KMT2A | |
| SCHEMBL115975 | 0.83 | CASR (0.34) | CASRNR1I2HEXAHEXBMEN1 | |
| SCHEMBL113809 | 0.81 | P2RX3 (0.34) | CASRNR1I2ALDH1A1MEN1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120058893-A1 | HERBICIDALLY ACTIVE KETOSULTAMS AND DIKETOPYRIDINES | BAYER CROPSCIENCE AG (DE) | 2012-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120058893-A1 | HERBICIDALLY ACTIVE KETOSULTAMS AND DIKETOPYRIDINES | KHK, KCNA1, KCNA2 | CASR 4298/4885NR1I2 2192/4885HEXA 747/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.