Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.65 |
| ▸ | LMNA | P02545 | 3/20 | 0.65 |
| ▸ | MAPT | P10636 | 3/20 | 0.65 |
| ▸ | TP53 | P04637 | 1/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.65 |
| ▸ | ACHE | P22303 | 7/20 | 0.62 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.57 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.57 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.57 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.57 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.57 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.57 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6884771 | 0.90 | LMNA (0.78) | ALDH1A1LMNAMAPTTP53TDP1 | |
| SCHEMBL8595734 | 0.90 | ALDH1A1 (0.64) | ALDH1A1LMNAMAPTTP53TDP1 | |
| SCHEMBL13471139 | 0.89 | ALDH1A1 (0.63) | ALDH1A1LMNAMAPTTP53TDP1 | |
| SCHEMBL12240152 | 0.88 | ALDH1A1 (0.62) | ALDH1A1LMNAMAPTTP53TDP1 | |
| SCHEMBL27209464 | 0.87 | PRKAB2 (0.70) | ALDH1A1LMNAMAPTTP53TDP1 | |
| SCHEMBL29721489 | 0.87 | PRKAB2 (0.70) | ALDH1A1LMNAMAPTTP53TDP1 | |
| SCHEMBL23630123 | 0.86 | ACHE (0.56) | ALDH1A1LMNAMAPTTP53TDP1 | |
| SCHEMBL31075717 | 0.86 | ACHE (0.56) | ALDH1A1LMNAMAPTTP53TDP1 | |
| SCHEMBL11130615 | 0.85 | LMNA (0.59) | ALDH1A1LMNAMAPTTP53TDP1 | |
| SCHEMBL23515721 | 0.83 | ALDH1A1 (0.55) | ALDH1A1LMNAMAPTTP53TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4167565-A | Adenosine-5'-carboxamides and method of use | ABBOTT LABORATORIES (US) | 1979-09-11 | — | — | US | disclosed |
| US-3992531-A | 2-Substituted adenosine-5'-carboxylates in the treatment of anginal pain | ABBOTT LABORATORIES (US) | 1976-11-16 | — | — | US | disclosed |