Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | RPS6KA2 | Q15349 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | KCNH3 | Q9ULD8 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | PLEC | Q15149 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2064760 | 0.84 | MAPT (0.57) | MAPTRPS6KA2GAAKCNH3ALDH1A1 | |
| SCHEMBL23366111 | 0.82 | IDO1 (0.46) | IDO1MAPTRPS6KA2GAAKCNH3 | |
| SCHEMBL6002300 | 0.78 | MAPT (0.73) | IDO1MAPTRPS6KA2GAAALDH1A1 | |
| SCHEMBL9167445 | 0.78 | APP (0.48) | MAPTGAAALDH1A1MEN1KMT2A | |
| SCHEMBL416817 | 0.77 | APP (0.47) | MAPTRPS6KA2GAAKCNH3ALDH1A1 | |
| SCHEMBL790635 | 0.77 | ALDH1A1 (0.64) | IDO1MAPTALDH1A1HDAC6 | |
| SCHEMBL1130358 | 0.76 | L3MBTL1 (0.43) | MAPTGAAALDH1A1TAAR1 | |
| SCHEMBL9191846 | 0.76 | MAPT (0.50) | MAPTGAAALDH1A1 | |
| SCHEMBL2089878 | 0.75 | MAPT (0.42) | MAPTRPS6KA2GAAKCNH3ALDH1A1 | |
| SCHEMBL295193 | 0.75 | KCNH3 (0.54) | MAPTRPS6KA2GAAKCNH3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4148815-A | Amino-thiol nickel and cobalt solvent extraction | KENNECOTT COPPER CORPORATION (US) | 1979-04-10 | — | — | US | claimed |
| US-4148815-A | Amino-thiol nickel and cobalt solvent extraction | KENNECOTT COPPER CORPORATION (US) | 1979-04-10 | — | — | US | disclosed |