Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.46 |
| ▸ | RPS6KA2 | Q15349 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KCNH3 | Q9ULD8 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | PLEC | Q15149 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11516786 | 0.82 | IDO1 (0.44) | IDO1RPS6KA2MAPTKCNH3ALDH1A1 | |
| SCHEMBL2064760 | 0.80 | MAPT (0.57) | RPS6KA2MAPTKCNH3ALDH1A1MEN1 | |
| SCHEMBL16526575 | 0.74 | RPS6KA2 (0.41) | IDO1RPS6KA2MAPTKCNH3ALDH1A1 | |
| SCHEMBL416817 | 0.74 | APP (0.47) | RPS6KA2MAPTKCNH3ALDH1A1MEN1 | |
| SCHEMBL2096635 | 0.74 | RPS6KA2 (0.41) | IDO1RPS6KA2MAPTKCNH3ALDH1A1 | |
| SCHEMBL378330 | 0.74 | MAPT (0.48) | RPS6KA2MAPTKCNH3ALDH1A1MEN1 | |
| SCHEMBL12652043 | 0.74 | IDO1 (0.46) | IDO1MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL14145331 | 0.74 | MAOA (0.43) | IDO1RPS6KA2MAPTKCNH3ALDH1A1 | |
| SCHEMBL12652046 | 0.73 | KIF11 (0.47) | MAPTMEN1KMT2ALMNACA1 | |
| SCHEMBL820286 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11008290-B2 | Halogenated quinoline derivatives as antimicrobial agents | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2021-05-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11008290-B2 | Halogenated quinoline derivatives as antimicrobial agents | NDUFS5, NDUFS7, NDUFS3 | IDO1 29/4885RPS6KA2 3751/4885MAPT 4764/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.