Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | DRD4 | P21917 | 1/20 | 0.48 |
| ▸ | DRD3 | P35462 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 2/20 | 0.43 |
| ▸ | NOS1 | P29475 | 4/20 | 0.41 |
| ▸ | AXL | P30530 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.40 |
| ▸ | METAP2 | P50579 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9534794 | 1.00 | ALDH1A1 (0.49) | ALDH1A1GLADRD2DRD4DRD3 | |
| SCHEMBL11508884 | 0.78 | IDO1 (0.47) | ALDH1A1GLACYP3A4TP53TSHR | |
| SCHEMBL729501 | 0.78 | ALDH1A1 (0.65) | ALDH1A1GLACYP3A4TP53TSHR | |
| SCHEMBL7679677 | 0.78 | ALDH1A1 (0.38) | ALDH1A1GLADRD2DRD4DRD3 | |
| SCHEMBL7679673 | 0.78 | ALDH1A1 (0.38) | ALDH1A1GLADRD2DRD4DRD3 | |
| SCHEMBL1499352 | 0.77 | ALDH1A1 (0.51) | ALDH1A1GLADRD2DRD4DRD3 | |
| SCHEMBL5756503 | 0.77 | ALDH1A1 (0.51) | ALDH1A1GLADRD2DRD4DRD3 | |
| SCHEMBL7884121 | 0.77 | ALDH1A1 (0.51) | ALDH1A1GLADRD2DRD4DRD3 | |
| SCHEMBL29989447 | 0.77 | ALDH1A1 (0.51) | ALDH1A1GLADRD2DRD4DRD3 | |
| SCHEMBL11517337 | 0.76 | ALDH1A1 (0.48) | ALDH1A1GLACYP3A4TP53TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11173144-B2 | Adrenergic receptor modulating compounds and methods of using the same | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2021-11-16 | — | — | US | disclosed |
| US-20200237724-A1 | ADRENERGIC RECEPTOR MODULATING COMPOUNDS AND METHODS OF USING THE SAME | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY | 2020-07-30 | — | — | US | disclosed |
| US-6534504-B1 | Increasing the quantity of meat or improving the quality of meat obtained from a livestock animal, comprising administering to the animal an effective amount of a compound represented by the following structural formula: | ELI LILLY AND COMPANY | 2003-03-18 | — | — | US | disclosed |
| WO-2001036390-A1 | INDAZOLYLOXY PROPANOLAMINES FOR IMPROVING LIVESTOCK PRODUCTION | ELI LILLY AND COMPANY (US) | 2001-05-25 | — | — | WO | disclosed |
| WO-2001035947-A2 | TREATING WASTING SYNDROMES WITH ARYLOXY PROPANOLAMINES | ELI LILLY AND COMPANY (US) | 2001-05-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200237724-A1 | ADRENERGIC RECEPTOR MODULATING COMPOUNDS AND METHODS OF USING THE SAME | ADRB1, ADRB2, ADRA1B | ALDH1A1 1787/4885GLA 2014/4885DRD2 396/4885 |
| US-11173144-B2 | Adrenergic receptor modulating compounds and methods of using the same | ADRB1, ADRB2, ADRA1B | ALDH1A1 1787/4885GLA 2014/4885DRD2 396/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.