Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2C | P18825 | 1/20 | 0.54 |
| ▸ | CXCL8 | P10145 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.52 |
| ▸ | SUCNR1 | Q9BXA5 | 3/20 | 0.51 |
| ▸ | F11 | P03951 | 2/20 | 0.51 |
| ▸ | CFD | P00746 | 2/20 | 0.51 |
| ▸ | TPSB2 | P20231 | 1/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.50 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.50 |
| ▸ | UGT1A9 | O60656 | 1/20 | 0.50 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.50 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.50 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.50 |
| ▸ | TTR | P02766 | 1/20 | 0.50 |
| ▸ | ALB | P02768 | 1/20 | 0.50 |
| ▸ | UGT1A6 | P19224 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9724473 | 0.84 | CXCL8 (0.57) | CXCL8ALDH1A1HPGDNR1H4SUCNR1 | |
| SCHEMBL15669253 | 0.83 | ADRA2C (0.51) | ADRA2CALDH1A1HPGDCA1CA2 | |
| SCHEMBL8860337 | 0.82 | CXCL8 (0.59) | CXCL8NR1H4SUCNR1F11CFD | |
| Hydrochloric Acid SCHEMBL5144329 | 0.80 | CXCL8 (0.57) | CXCL8NR1H4SUCNR1F11CFD | |
| SCHEMBL23229080 | 0.80 | MAPK1 (0.61) | CXCL8ALDH1A1HPGDNR1H4PTGS2 | |
| SCHEMBL5270832 | 0.79 | SUCNR1 (0.56) | CXCL8NR1H4SUCNR1F11CFD | |
| SCHEMBL3054871 | 0.79 | NR1H4 (0.59) | CXCL8ALDH1A1HPGDNR1H4PTGS2 | |
| SCHEMBL31226210 | 0.79 | NR1H4 (0.59) | CXCL8ALDH1A1HPGDNR1H4PTGS2 | |
| SCHEMBL21711305 | 0.77 | NR1H4 (0.75) | CXCL8HPGDNR1H4SUCNR1F11 | |
| SCHEMBL5056014 | 0.76 | NPC1 (0.59) | ALDH1A1SUCNR1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4155905-A | 6-Substituted penicillanic acid and derivatives thereof | E. R. SQUIBB & SONS, INC. (US) | 1979-05-22 | — | — | US | disclosed |
| US-4077967-A | 6-Substituted penicillanic acid and derivatives thereof | E. R. SQUIBB & SONS, INC. (US) | 1978-03-07 | — | — | US | disclosed |
| US-4061629-A | 6-Amino-6-arylthio penicillanic acids and derivatives thereof | E. R. SQUIBB & SONS, INC. (US) | 1977-12-06 | — | — | US | disclosed |
| US-4061851-A | 7-Amino-7-arylthio cephalosporins | E. R. SQUIBB & SONS, INC. (US) | 1977-12-06 | — | — | US | disclosed |
| US-4029669-A | 6-Benzalimino-6-arylthio penicillanic acids and derivatives thereof | E. R. SQUIBB & SONS, INC. (US) | 1977-06-14 | — | — | US | disclosed |
| US-4026886-A | 7-Acyl-7-arylthiocephalosporins | E. R. SQUIBB & SONS, INC. (US) | 1977-05-31 | — | — | US | disclosed |
| US-3965093-A | 6-Arylthio penicillanic acid and derivatives thereof | E. R. SQUIBB & SONS, INC. (US) | 1976-06-22 | — | — | US | disclosed |
| US-3954744-A | ANTIBACTERIAL | E. R. SQUIBB & SONS, INC. (US) | 1976-05-04 | — | — | US | disclosed |