Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCL8 | P10145 | 4/20 | 0.57 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.56 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.54 |
| ▸ | TTR | P02766 | 2/20 | 0.54 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.54 |
| ▸ | UGT1A9 | O60656 | 1/20 | 0.54 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.54 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.54 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.54 |
| ▸ | ALB | P02768 | 1/20 | 0.54 |
| ▸ | UGT1A6 | P19224 | 1/20 | 0.54 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.54 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.54 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.54 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.54 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.54 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.54 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.54 |
| ▸ | UGT1A7 | Q9HAW7 | 1/20 | 0.54 |
| ▸ | UGT1A10 | Q9HAW8 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5270832 | 0.95 | SUCNR1 (0.56) | CXCL8NR1H4PTGS2TTRAKR1B10 | |
| Benzaldehyde SCHEMBL11554981 | 0.89 | NR1H4 (0.48) | CXCL8NR1H4PTGS2TTRAKR1B10 | |
| SCHEMBL8860337 | 0.86 | CXCL8 (0.59) | CXCL8NR1H4PTGS2TTRAKR1B10 | |
| Hydrochloric Acid SCHEMBL5144329 | 0.85 | CXCL8 (0.57) | CXCL8NR1H4PTGS2TTRAKR1B10 | |
| SCHEMBL11517893 | 0.84 | ADRA2C (0.54) | CXCL8NR1H4PTGS2TTRAKR1B10 | |
| SCHEMBL3054871 | 0.83 | NR1H4 (0.59) | CXCL8NR1H4PTGS2TTRAKR1B10 | |
| SCHEMBL31226210 | 0.83 | NR1H4 (0.59) | CXCL8NR1H4PTGS2TTRAKR1B10 | |
| SCHEMBL10967695 | 0.83 | GAA (0.46) | CXCL8NR1H4PTGS2TTRAKR1B10 | |
| SCHEMBL5151913 | 0.83 | SUCNR1 (0.60) | CXCL8NR1H4PTGS2SUCNR1CFD | |
| SCHEMBL465541 | 0.82 | GAA (0.52) | ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0045523-B1 | ALPHA-SUBSTITUTED UREIDOBENZYLPENICILLANIC ACID DERIVATIVES AND PROCESS FOR PRODUCING THE SAME | Chugai Seiyaku Kabushiki Kaisha (JP) | 1984-12-05 | — | — | EP | claimed |
| EP-0045523-A1 | Alpha-substituted ureidobenzylpenicillanic acid derivatives and process for producing the same | Chugai Seiyaku Kabushiki Kaisha (JP) | 1982-02-10 | — | — | EP | claimed |
| JP-58135890-A | — | — | None | — | — | JP | disclosed |
| JP-57032289-A | — | — | None | — | — | JP | disclosed |
| JP-55031044-A | — | — | None | — | — | JP | disclosed |
| JP-55036411-A | — | — | None | — | — | JP | disclosed |
| JP-55143995-A | — | — | None | — | — | JP | disclosed |
| JP-56040687-A | — | — | None | — | — | JP | disclosed |
| JP-4235165-A | — | — | None | — | — | JP | disclosed |
| CN-101973941-B | Method for preparing 4-hydroxyphenyl hydantoin | TIANJIN VOCATIONAL INST | 2012-11-28 | — | — | CN | disclosed |
| CN-101973941-A | Method for preparing 4-hydroxyphenyl hydantoin | TIANJIN VOCATIONAL INST | 2011-02-16 | — | — | CN | disclosed |
| JP-S5732289-A | ALPHA-SUBSTITUTED UREIDOBENZYLPENICILLIN | CHUGAI PHARMACEUT CO LTD | 1982-02-20 | — | — | JP | disclosed |
| EP-0045523-A1 | Alpha-substituted ureidobenzylpenicillanic acid derivatives and process for producing the same | Chugai Seiyaku Kabushiki Kaisha (JP) | 1982-02-10 | — | — | EP | disclosed |
| US-4301161-A | BACTERICIDES | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1981-11-17 | — | — | US | disclosed |
| US-4298605-A | ANTIBIOTICS, BACTERICIDES | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1981-11-03 | — | — | US | disclosed |
| JP-S5640687-A | PREPARATION OF PENICILLANIC ACID DERIVATIVE OR ITS SALT | CHUGAI PHARMACEUT CO LTD | 1981-04-16 | — | — | JP | disclosed |
| JP-S55143995-A | CEPHALOSPORIN DERIVATIVE AND ITS PREPARATION | CHUGAI PHARMACEUT CO LTD | 1980-11-10 | — | — | JP | disclosed |
| US-4229348-A | Penicillanic acid derivatives | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1980-10-21 | — | — | US | disclosed |
| JP-S5536411-A | BENZYLPENICILLIN DERIVATIVE AND THEIR PREPARATION | CHUGAI PHARMACEUT CO LTD | 1980-03-14 | — | — | JP | disclosed |
| JP-S5531044-A | PENICILLANIC ACID DERIVATIVE AND ITS PREPARATION | CHUGAI PHARMACEUT CO LTD | 1980-03-05 | — | — | JP | disclosed |