SCHEMBL8860337

SCHEMBL8860337

NNc1ccccc1CC(=O)O

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CXCL8 P10145 5/20 0.59
PTGS2 P35354 4/20 0.56
NR1H4 Q96RI1 2/20 0.56
TTR P02766 2/20 0.56
AKR1B10 O60218 1/20 0.56
UGT1A9 O60656 1/20 0.56
TRPA1 O75762 1/20 0.56
ABCB11 O95342 1/20 0.56
MT-CO2 P00403 1/20 0.56
ALB P02768 1/20 0.56
UGT1A6 P19224 1/20 0.56
UGT1A1 P22309 1/20 0.56
PTGS1 P23219 1/20 0.56
CXCR1 P25024 1/20 0.56
ADRA1A P35348 1/20 0.56
AGTR2 P50052 1/20 0.56
NR1I3 Q14994 1/20 0.56
SLC22A6 Q4U2R8 1/20 0.56
UGT1A7 Q9HAW7 1/20 0.56
UGT1A10 Q9HAW8 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL5144329 0.98 CXCL8 (0.57) CXCL8PTGS2NR1H4TTRAKR1B10
SCHEMBL9724473 0.86 CXCL8 (0.57) CXCL8PTGS2NR1H4TTRAKR1B10
SCHEMBL5270832 0.82 SUCNR1 (0.56) CXCL8PTGS2NR1H4TTRAKR1B10
SCHEMBL11517893 0.82 ADRA2C (0.54) CXCL8PTGS2NR1H4TTRAKR1B10
SCHEMBL7683559 0.82 CXCL8 (0.61) CXCL8PTGS2NR1H4TTRAKR1B10
SCHEMBL11175115 0.81 KEAP1 (0.48) CXCL8ADRA1A
SCHEMBL3054871 0.81 NR1H4 (0.59) CXCL8PTGS2NR1H4TTRAKR1B10
SCHEMBL31226210 0.81 NR1H4 (0.59) CXCL8PTGS2NR1H4TTRAKR1B10
SCHEMBL11042891 0.80 CXCL8 (0.64) CXCL8PTGS2NR1H4TTRAKR1B10
SCHEMBL1964864 0.80 PTGS2 (0.60) CXCL8PTGS2NR1H4TTRAKR1B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117956878-A Perovskite layer manufacturing method, perovskite battery, battery assembly and photovoltaic system 浙江爱旭太阳能科技有限公司 2024-04-30 CN claimed
CN-117956878-A Perovskite layer manufacturing method, perovskite battery, battery assembly and photovoltaic system 浙江爱旭太阳能科技有限公司 2024-04-30 CN disclosed
US-5686626-A COGNITION ACTIVATORS HOECHST MARION ROUSSEL, INC. (US) 1997-11-11 US disclosed
US-5621116-A CHEMICAL INTERMEDIATES; MEMORY ENHANCERS FOR TREATMENT OF ALZHEIMER*S, ANALGESICS, ANTICONVULSANTS HOECHST MARION ROUSSEL, INC. (US) 1997-04-15 US disclosed
US-5464846-A Learning enhancement, Alzheimer's disease HOECHST-ROUSSEL PHARMACEUTICALS, INC. (US) 1995-11-07 US disclosed
EP-0415103-B1 2,3-Dihydro-1-(pyridinylamino)-indoles, a process for their preparation and their use as medicaments HOECHST ROUSSEL PHARMA (US) 1995-02-01 EP disclosed
EP-0415102-B1 1,3-Dihydro-1-(pyridinylamino)-2H-indol-2-ones, a process for their preparation and their use as medicaments HOECHST ROUSSEL PHARMA (US) 1995-02-01 EP disclosed
US-5296488-A Method of using 2,3-dihydro-1-(pyridinylamino)-indoles as anticonvulsants and for the enhancement of memory HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) 1994-03-22 US disclosed
US-5179119-A Cognition activators; alzheimer*s disease HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) 1993-01-12 US disclosed
US-5179099-A Analgesics HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) 1993-01-12 US disclosed
US-5053511-A Analgesics; anticonvulsants; treatment for alzheimers disease HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) 1991-10-01 US disclosed
US-5006537-A Analgesics, memory enhancement, Alzheimer* disease HOECHST-ROUSSEL PHARMACEUTICALS, INC. (US) 1991-04-09 US disclosed
EP-0415102-A1 1,3-Dihydro-1-(pyridinylamino)-2H-indol-2-ones, a process for their preparation and their use as medicaments HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) 1991-03-06 EP disclosed
EP-0415103-A1 2,3-Dihydro-1-(pyridinylamino)-indoles, a process for their preparation and their use as medicaments HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) 1991-03-06 EP disclosed
EP-0142012-B1 PROCESS AND MEANS FOR THE PRODUCTION OF WHITE AND COLOURED RESERVE PRINTS ON TEXTILES MADE OF HYDROPHOBIC SYNTHETIC FIBROUS MATERIALS HOECHST AKTIENGESELLSCHAFT (DE) 1986-12-17 EP disclosed
EP-0184101-A2 Composition for the production of white and coloured discharges on synthetic hydrophilic fibre material HOECHST AKTIENGESELLSCHAFT (DE) 1986-06-11 EP disclosed
EP-0142012-A1 Process and means for the production of white and coloured reserve prints on textiles made of hydrophobic synthetic fibrous materials HOECHST AKTIENGESELLSCHAFT (DE) 1985-05-22 EP disclosed
EP-0031951-B1 FORMYL DERIVATIVES OF HYDRAZINOMETHYLPENICILLINS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS CRAF Sud (IT) 1984-07-25 EP disclosed
US-4459227-A Para-hydroxyphenylhydrazines as in situ precursors of iminoquinones and quinones DUKE UNIVERSITY (US) 1984-07-10 US disclosed
US-4239901-A ANALGESICS, ANTIPYRETICS, ANTIINFLAMMATORY AGENTS BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) 1980-12-16 US disclosed