SCHEMBL11517898

SCHEMBL11517898

O=C1OC(=O)c2cc(N3C(=O)CCCC3=O)ccc21

nearest known ligand 0.49

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.49
L3MBTL1 Q9Y468 1/20 0.42
LMNA P02545 4/20 0.41
ALDH1A1 P00352 3/20 0.41
MAPT P10636 4/20 0.40
ALOX15 P16050 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
MEN1 O00255 3/20 0.37
SMN1; SMN2 Q16637 2/20 0.36
POLB P06746 2/20 0.36
CA12 O43570 2/20 0.36
CA1 P00915 2/20 0.36
CA9 Q16790 2/20 0.36
CA2 P00918 1/20 0.35
KDM4E B2RXH2 1/20 0.34
HTT P42858 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11517116 0.93 L3MBTL1 (0.49) KMT2AL3MBTL1LMNAALDH1A1ALOX15
SCHEMBL10689686 0.77 ALDH1A1 (0.56) KMT2AL3MBTL1LMNAALDH1A1MAPT
SCHEMBL6252262 0.77 MGLL (0.55) ALDH1A1TDP1HTT
SCHEMBL10688892 0.75 ALDH1A1 (0.54) KMT2AL3MBTL1LMNAALDH1A1MAPT
SCHEMBL25557002 0.74 ALDH1A1 (0.49) KMT2AL3MBTL1LMNAALDH1A1MAPT
SCHEMBL10934428 0.74 PARP1 (0.46) KMT2AL3MBTL1ALDH1A1ALOX15TDP1
SCHEMBL24534305 0.73 ALDH1A1 (0.56) KMT2AL3MBTL1ALDH1A1MAPTALOX15
SCHEMBL6140528 0.69 KMT2A (0.62) KMT2AL3MBTL1LMNAALDH1A1MAPT
SCHEMBL11510205 0.69 MEN1 (0.38) KMT2AL3MBTL1LMNAALDH1A1MAPT
SCHEMBL718072 0.69 KMT2A (0.63) KMT2AL3MBTL1LMNAALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4160081-A Imidyl- and isoimidyl-phthalic anhydrides, process for their manufacture and their use for curing epoxide resins CIBA-GEIGY CORPORATION (US) 1979-07-03 US disclosed
US-4131613-A CURING AGENTS FOR EPOXIDE RESINS CIBA-GEIGY CORPORATION (US) 1978-12-26 US disclosed
US-3979393-A Imidyl- and isoimidyl-phthalic anhydrides, process for their manufacture and their use for curing epoxide resins CIBA-GEIGY CORPORATION (US) 1976-09-07 US disclosed