Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | APEX1 | P27695 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 6/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.51 |
| ▸ | RAB9A | P51151 | 5/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11379700 | 0.78 | SMN1; SMN2 (0.58) | KMT2AALDH1A1MEN1POLBTHRB | |
| SCHEMBL3905239 | 0.76 | NPC1 (0.41) | KMT2AALDH1A1MEN1POLBNPC1 | |
| SCHEMBL7932102 | 0.75 | ALDH1A1 (0.63) | KMT2AALDH1A1MEN1POLBTHRB | |
| SCHEMBL28335108 | 0.75 | KMT2A (0.59) | KMT2AALDH1A1MEN1POLBTDP1 | |
| SCHEMBL5635022 | 0.73 | UHRF1 (0.46) | KMT2AALDH1A1MEN1NPC1SMN1; SMN2 | |
| SCHEMBL3948156 | 0.72 | POLB (0.49) | KMT2AALDH1A1MEN1POLBTHRB | |
| SCHEMBL11756461 | 0.72 | ALDH1A1 (0.58) | KMT2AALDH1A1MEN1POLBTHRB | |
| SCHEMBL28533406 | 0.72 | ALDH1A1 (0.58) | KMT2AALDH1A1MEN1POLBTHRB | |
| SCHEMBL181841 | 0.72 | ALDH1A1 (0.74) | KMT2AALDH1A1MEN1POLBTHRB | |
| SCHEMBL397492 | 0.71 | ALDH1A1 (0.52) | KMT2AALDH1A1MEN1NPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4173705-A | ANALGESIC | LABORATORIOS MADE, S.A. (ES) | 1979-11-06 | — | — | US | claimed |
| US-4173705-A | ANALGESIC | LABORATORIOS MADE, S.A. (ES) | 1979-11-06 | — | — | US | disclosed |
| US-4173705-A | ANALGESIC | LABORATORIOS MADE, S.A. (ES) | 1979-11-06 | — | — | US | disclosed |
| US-4173705-A | ANALGESIC | LABORATORIOS MADE, S.A. (ES) | 1979-11-06 | — | — | US | disclosed |