Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 7/20 | 0.58 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.58 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.58 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.58 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.58 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.58 |
| ▸ | HTR1A | P08908 | 2/20 | 0.58 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.58 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.58 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.58 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.58 |
| ▸ | DRD2 | P14416 | 2/20 | 0.58 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6596304 | 1.00 | LMNA (0.58) | LMNAHIF1ACYP2D6MAPK1CYP3A4 | |
| SCHEMBL1151817 | 1.00 | LMNA (0.58) | LMNAHIF1ACYP2D6MAPK1CYP3A4 | |
| SCHEMBL9530000 | 1.00 | LMNA (0.58) | LMNAHIF1ACYP2D6MAPK1CYP3A4 | |
| Hydrochloric Acid SCHEMBL3842618 | 0.98 | LMNA (0.56) | LMNAHIF1ACYP2D6MAPK1CYP3A4 | |
| Hydrochloric Acid SCHEMBL3842615 | 0.98 | LMNA (0.56) | LMNAHIF1ACYP2D6MAPK1CYP3A4 | |
| Fluoride SCHEMBL27904711 | 0.98 | LMNA (0.56) | LMNAHIF1ACYP2D6MAPK1CYP3A4 | |
| SCHEMBL9123051 | 0.94 | LTA4H (0.59) | LMNAHIF1ACYP2D6MAPK1CYP3A4 | |
| SCHEMBL11661323 | 0.94 | LTA4H (0.59) | LMNAHIF1ACYP2D6MAPK1CYP3A4 | |
| SCHEMBL27901883 | 0.90 | LMNA (0.51) | LMNAHIF1ACYP2D6MAPK1CYP3A4 | |
| SCHEMBL27901884 | 0.90 | LMNA (0.51) | LMNAHIF1ACYP2D6MAPK1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 433 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120058618-A | Antitumor cinnamyl piperazine and 2-phenylbenzimidazole conjugate, and preparation method and application thereof | 天津科技大学 | 2025-05-30 | — | — | CN | claimed |
| CN-119708027-A | Method for preparing boronated carbonyl derivative | 中国科学院大连化学物理研究所 | 2025-03-28 | — | — | CN | claimed |
| CN-119219575-B | Antitumor cinnamyl piperazine resveratrol conjugate or pharmaceutically acceptable salt thereof, and preparation method and application thereof | 天津科技大学 | 2025-03-11 | — | — | CN | claimed |
| CN-119219575-A | Antitumor cinnamyl piperazine resveratrol conjugate or pharmaceutically acceptable salt thereof, and preparation method and application thereof | 天津科技大学 | 2024-12-31 | — | — | CN | claimed |
| CN-110967421-B | Method for detecting related substances of flunarizine hydrochloride preparation | 正大青春宝药业有限公司 | 2022-04-12 | — | — | CN | claimed |
| CN-114276402-A | Steroid derivative and application thereof in preparation of antitumor drugs | 厦门大学 | 2022-04-05 | — | — | CN | claimed |
| CN-110967421-A | Method for detecting related substances of flunarizine hydrochloride preparation | 正大青春宝药业有限公司 | 2020-04-07 | — | — | CN | claimed |
| CN-108126656-A | For the modified activated carbon absorbent of benzene in Adsorption wastewater from chemical industry | 北京益清源环保科技有限公司 | 2018-06-08 | — | — | CN | claimed |
| CN-106366051-A | Synthesis method of cinnamyl piperazine | 郑州瑞康制药有限公司 | 2017-02-01 | — | — | CN | claimed |
| CN-103172593-B | A kind of preparation technology of CN | Zhuzhou Bonded Zone Lizhu Synthetic Pharmaceutical Co., Ltd. (CN) | 2016-01-27 | — | — | CN | claimed |
| EP-0551617-A2 | Cinnamyl piperazine derivatives method of manufacturing the same and agricultural/horticultural fungicides containing cinnamyl piperazine derivatives | UBE INDUSTRIES, LTD. (JP) | 1993-07-21 | — | — | EP | claimed |
| EP-0319983-B1 | ASSOCIATION OF PYRIMIDINE DERIVATIVES AND CALCIUM ANTAGONISTS TO INDUCE AND STIMULATE THE HAIR GROWTH AND TO REDUCE HAIR LOSS | L'OREAL (FR) | 1992-06-03 | — | — | EP | claimed |
| US-5059606-A | COMBINATION OF PYRIMIDINE DERIVATIVES AND CALCIUM ANTAGONISTS TO INDUCE AND STIMULATE HAIR GROWTH AND REDUCE HAIR LOSS | L'OREAL (FR) | 1991-10-22 | — | — | US | claimed |
| EP-0322643-A1 | Medicines containing as a mixture interferon and 1-desoxy-piperidinoses, process for their manufacture and their use | BAYER AG (DE) | 1989-07-05 | — | — | EP | claimed |
| EP-0319983-A1 | Association of pyrimidine derivatives and calcium antagonists to induce and stimulate the hair growth and to reduce hair loss | L'OREAL (FR) | 1989-06-14 | — | — | EP | claimed |
| EP-0313974-A1 | N-substituted derivatives of 1-desoxynojirimycine and 1-desoxymannonojirimycine, process for their preparation and their use as pharmaceuticals | BAYER AG (DE) | 1989-05-03 | — | — | EP | claimed |
| CN-85102263-B | New process for synthesizing neobrain-benefiting oxazine | 郑州大学 | 1988-03-23 | — | — | CN | claimed |
| CN-86105558-A | The preparation method of new (4-replaces-piperazinyl) pyridazine class | — | 1987-01-28 | — | — | CN | claimed |
| CN-85102263-A | Synthetic technique for \" new cinnarizine \ | — | 1986-05-10 | — | — | CN | claimed |
| EP-0142756-A2 | Methyl-piperazino derivatives with analgesic activity, a process for their preparation, and therapeutic compounds which contain them | EURORESEARCH S.R.L. (IT) | 1985-05-29 | — | — | EP | claimed |