Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 7/20 | 0.58 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.58 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.58 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.58 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.58 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.58 |
| ▸ | HTR1A | P08908 | 2/20 | 0.58 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.58 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.58 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.58 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.58 |
| ▸ | DRD2 | P14416 | 2/20 | 0.58 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1151817 | 1.00 | LMNA (0.58) | LMNAHIF1ACYP2D6MAPK1CYP3A4 | |
| SCHEMBL9530000 | 1.00 | LMNA (0.58) | LMNAHIF1ACYP2D6MAPK1CYP3A4 | |
| SCHEMBL1151821 | 1.00 | LMNA (0.58) | LMNAHIF1ACYP2D6MAPK1CYP3A4 | |
| Fluoride SCHEMBL27904711 | 0.98 | LMNA (0.56) | LMNAHIF1ACYP2D6MAPK1CYP3A4 | |
| Hydrochloric Acid SCHEMBL3842618 | 0.98 | LMNA (0.56) | LMNAHIF1ACYP2D6MAPK1CYP3A4 | |
| Hydrochloric Acid SCHEMBL3842615 | 0.98 | LMNA (0.56) | LMNAHIF1ACYP2D6MAPK1CYP3A4 | |
| SCHEMBL9123051 | 0.94 | LTA4H (0.59) | LMNAHIF1ACYP2D6MAPK1CYP3A4 | |
| SCHEMBL11661323 | 0.94 | LTA4H (0.59) | LMNAHIF1ACYP2D6MAPK1CYP3A4 | |
| SCHEMBL27901884 | 0.90 | LMNA (0.51) | LMNAHIF1ACYP2D6MAPK1CYP3A4 | |
| SCHEMBL27901883 | 0.90 | LMNA (0.51) | LMNAHIF1ACYP2D6MAPK1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1069124-B1 | 2-Benzimidazolylamine compounds as ORL1-receptor agonists | PFIZER (US) | 2004-05-12 | — | — | EP | disclosed |
| US-20020128231-A1 | Aryl-indane compounds | EASTMAN CHEMICAL COMPANY | 2002-09-12 | — | — | US | disclosed |
| WO-2002030915-A2 | ARYL-INDANE COMPOUNDS FOR USE AS INHIBITORS OF P-GLYCOPROTEIN MEDIATED TRANSPORT | AVLAN LIMITED (GB) | 2002-04-18 | — | — | WO | disclosed |
| US-6340681-B1 | USEFUL AS ANALGESICS IN MAMMALS | PFIZER INC | 2002-01-22 | — | — | US | disclosed |
| US-5395934-A | Antiarrhythmia agents and cardiovascular disorders | EGIS GYOGYSZERGYAR (HU) | 1995-03-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020128231-A1 | Aryl-indane compounds | ABCB1, ABCC1, ABCG2 | LMNA 4136/4885HIF1A 2851/4885CYP2D6 142/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.