SCHEMBL115193

SCHEMBL115193

CC[Si](Cl)(Cl)c1ccccc1

nearest known ligand 0.38

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.38
ESR1 P03372 2/20 0.34
ESR2 Q92731 1/20 0.34
PSIP1 O75475 1/20 0.32
MAPT P10636 1/20 0.31
KDM4E B2RXH2 1/20 0.31
ALDH1A1 P00352 1/20 0.31
GAA P10253 1/20 0.31
HPGD P15428 1/20 0.31
LMNA P02545 2/20 0.31
TSHR P16473 2/20 0.30
ALOX12 P18054 1/20 0.30
ACHE P22303 1/20 0.30
ATM Q13315 1/20 0.30
CYP19A1 P11511 1/20 0.30
KCNN4 O15554 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Naphthalene SCHEMBL28055828 0.93 CYP2A6 (0.36) TP53ESR1ESR2KDM4EALDH1A1
SCHEMBL11128894 0.91 ESR1 (0.34) TP53ESR1ESR2MAPT
Diphenylamine SCHEMBL7525400 0.87 HSD17B10 (0.48) MAPTKDM4EALDH1A1GAAHPGD
SCHEMBL11200862 0.86 KIF11 (0.41) ESR1MAPTKDM4EALDH1A1HPGD
SCHEMBL707866 0.86 ESR1 (0.40) ESR1ESR2
SCHEMBL6748571 0.85 TP53 (0.38) TP53KDM4EALDH1A1TSHRCYP19A1
SCHEMBL6751471 0.83 ALDH1A1 (0.43) MAPTKDM4EALDH1A1LMNATSHR
SCHEMBL15209480 0.82
SCHEMBL8693286 0.81 LTA4H (0.52) HPGDLMNATSHR
SCHEMBL707143 0.80 TP53 (0.35) TP53ESR1ESR2PSIP1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 359 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114130212-B Method for preparing separation membrane by using small molecular monomers 天津工业大学 2025-02-21 CN claimed
CN-118599118-A Energy-saving and consumption-reducing poly (ether) sulfone and method for synthesizing block copolymer thereof 山东净泽膜科技有限公司 2024-09-06 CN claimed
CN-117264215-A Method for synthesizing polysulfone, polyether sulfone and segmented copolymer thereof by dehydration synchronous polymerization 天津工业大学 2023-12-22 CN claimed
CN-112898757-B Method for preparing transparent toughened polylactic acid material based on silicone rubber microspheres 杭州卓普新材料科技有限公司 2022-06-07 CN claimed
CN-114130212-A Method for preparing separation membrane by using small molecule monomer 天津工业大学 2022-03-04 CN claimed
CN-112898757-A Method for preparing transparent toughened polylactic acid material based on silicone rubber microspheres 杭州卓普新材料科技有限公司 2021-06-04 CN claimed
CN-110305457-B Preparation method of transparent toughened polylactic acid material 杭州卓普新材料科技有限公司 2021-04-30 CN claimed
CN-110305457-A Preparation method of transparent toughened polylactic acid material 杭州卓普新材料科技有限公司 2019-10-08 CN claimed
CN-103408758-B A kind of preparation method of ethyl phenyl silicone oil JIANGSU UNIVERSITY (CN) 2015-10-28 CN claimed
CN-103408758-A Preparation method of ethyl phenyl silicone oil UNIV JIANGSU 2013-11-27 CN claimed
WO-2006062219-A1 ULTRAVIOLET TRANSMISSIVE POLYHEDRAL SILSESQUIOXANE POLYMERS MATSUSHITA ELECTRIC WORKS, LTD. (JP) 2006-06-15 WO claimed
US-20060122351-A1 Ultraviolet transmissive polyhedral silsesquioxane polymers PANASONIC ELECTRIC WORKS CO., LTD. (JP) 2006-06-08 US claimed
EP-1546250-A2 ORGANOSILICON COMPOUNDS AND BLENDS FOR TREATING SILICA Dow Corning Corporation (US) 2005-06-29 EP claimed
WO-2004024812-A2 ORGANOSILICON COMPOUNDS AND BLENDS FOR TREATING SILICA DOW CORNING CORPORATION (US) 2004-03-25 WO claimed
US-6046293-A Solid-liquid phase interfacial polymerization UNIVERSITY OF SOUTH AUSTRALIA (AU) 2000-04-04 US claimed
EP-0799851-A2 Preparation of polyorganosilloxanes by interfacial polymerization DOW CORNING CORPORATION (US) 1997-10-08 EP claimed
US-5629401-A Preparation of polyorganosiloxanes by interfacial polymerization DOW CORNING CORPORATION (US) 1997-05-13 US claimed
US-5286891-A Hydrolysis of chloro-termianted polysilane SHIN-ETSU CHEMICAL CO., LTD. (JP) 1994-02-15 US claimed
US-4839451-A Processes for the preparation of polysilylenes XEROX CORPORATION (US) 1989-06-13 US claimed
EP-0231497-A1 Silicone resist materials containing polysiloxanes KABUSHIKI KAISHA TOSHIBA (JP) 1987-08-12 EP claimed