Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 2/20 | 0.61 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | MGLL | Q99685 | 1/20 | 0.44 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.41 |
| ▸ | HTR3B | O95264 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10999344 | 0.83 | CYP2C9 (0.63) | ADRB1ALOX5MAPTMEN1KMT2A | |
| SCHEMBL10999156 | 0.80 | ADRB1 (0.56) | ADRB1ALOX5MAPTMEN1KMT2A | |
| SCHEMBL15055212 | 0.80 | HTR3E (0.53) | ADRB1ALOX5MAPTL3MBTL1HSD17B10 | |
| SCHEMBL81365 | 0.76 | ADRB1 (1.00) | ADRB1MAPTKCNH2HTR3EHTR3B | |
| SCHEMBL29391951 | 0.76 | ADRB1 (1.00) | ADRB1MAPTKCNH2HTR3EHTR3B | |
| SCHEMBL28525066 | 0.76 | ADRB1 (0.37) | ADRB1ALOX5HTR3EHTR3BTP53 | |
| SCHEMBL29849718 | 0.76 | ADRB1 (0.37) | ADRB1ALOX5HTR3EHTR3BTP53 | |
| SCHEMBL150081 | 0.76 | ALOX5 (0.60) | ADRB1ALOX5MAPTL3MBTL1HSD17B10 | |
| SCHEMBL1459854 | 0.76 | L3MBTL1 (0.54) | ADRB1ALOX5MAPTL3MBTL1HSD17B10 | |
| Hydrochloric Acid SCHEMBL314399 | 0.75 | ADRB1 (0.96) | ADRB1MAPTKCNH2HTR3EHTR3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4162319-A | ANTHELMINTICS, PSYCHOTROPIC, CNS, HYPOGLYCOMIC AGENTS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1979-07-24 | — | — | US | disclosed |