Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | ADORA3 | P0DMS8 | 6/20 | 0.50 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.50 |
| ▸ | HSP90B1 | P14625 | 4/20 | 0.50 |
| ▸ | ADORA2B | P29275 | 4/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | TMIGD3 | P0DMS9 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | AHCY | P23526 | 1/20 | 0.46 |
| ▸ | PI4KA | P42356 | 1/20 | 0.45 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.45 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.45 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8954333 | 0.74 | GAA (1.00) | GAAADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL5944101 | 0.72 | ADORA3 (0.56) | ADORA3ADORA2AHSP90B1ADORA2BTSHR | |
| SCHEMBL5944284 | 0.71 | ADORA3 (0.53) | ADORA3ADORA2AHSP90B1ADORA2BTSHR | |
| SCHEMBL13689761 | 0.69 | ADORA3 (0.71) | ADORA3ADORA2AHSP90B1ADORA2BTSHR | |
| SCHEMBL13901807 | 0.69 | ADORA3 (0.71) | ADORA3ADORA2AHSP90B1ADORA2BTSHR | |
| SCHEMBL9024927 | 0.69 | PRMT5 (0.58) | ADORA3ADORA2AHSP90B1ADORA2BADORA1 | |
| SCHEMBL9024944 | 0.69 | PRMT5 (0.58) | ADORA3ADORA2AHSP90B1ADORA2BADORA1 | |
| SCHEMBL6297541 | 0.69 | PRMT5 (0.58) | ADORA3ADORA2AHSP90B1ADORA2BADORA1 | |
| SCHEMBL11518921 | 0.69 | PRMT5 (0.58) | ADORA3ADORA2AHSP90B1ADORA2BADORA1 | |
| SCHEMBL26739953 | 0.68 | GAA (0.55) | GAAADORA3ADORA2AHSP90B1ADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4167565-A | Adenosine-5'-carboxamides and method of use | ABBOTT LABORATORIES (US) | 1979-09-11 | — | — | US | disclosed |